Who are Anti-VEGF injections's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): REGORAFENIB, PONATINIB HYDROCHLORIDE, Inlyta, PAZOPANIB HYDROCHLORIDE, PAZOPANIB, Sutent.

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Last reviewed 2026-05-16 · How we verify

Anti-VEGF injections — Competitive Intelligence Brief

Anti-VEGF injections (Anti-VEGF injections) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Anti-angiogenic agent. Area: Oncology.

phase 2 Anti-angiogenic agent VEGF Oncology Small molecule Live · refreshed every 30 min

Target snapshot

Anti-VEGF injections (Anti-VEGF injections) — Bayer. Anti-VEGF injections work by binding to and inhibiting vascular endothelial growth factor (VEGF), a protein that promotes angiogenesis.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Anti-VEGF injections TARGET	Anti-VEGF injections	Bayer	phase 2	Anti-angiogenic agent	VEGF
REGORAFENIB	REGORAFENIB		marketed		RET, VEGFR1, VEGFR2, VEGFR3, KIT, PDGFR-alpha, PDGFR-beta, FGFR1, FGFR2, TIE2, DDR2, TrkA, Eph2A, RAF-1, BRAF, BRAF V600E, SAPK2, PTK5, Abl, CSF1R	2012-01-01
PONATINIB HYDROCHLORIDE	PONATINIB HYDROCHLORIDE		marketed		ABL, T315I mutant ABL, VEGFR, PDGFR, FGFR, EPH receptors, SRC family, KIT, RET, TIE2, FLT3	2012-01-01
Inlyta	Axitinib	Pfizer	marketed	Receptor tyrosine kinase inhibitor	Vascular endothelial growth factor receptors (VEGFR)-1, VEGFR-2, VEGFR-3	2012-01-01
PAZOPANIB HYDROCHLORIDE	PAZOPANIB HYDROCHLORIDE		marketed		VEGFR-1, VEGFR-2, VEGFR-3, PDGFR-α, PDGFR-β, FGFR-1, FGFR-3, Kit, Itk, Lck, c-Fms	2009-01-01
PAZOPANIB	PAZOPANIB		marketed	Kinase Inhibitor [EPC]	VEGFR-1, VEGFR-2, VEGFR-3, PDGFR-ɑ, PDGFR-β, FGFR-1, FGFR-3, Kit, Itk, Lck, c-Fms	2009-01-01
Sutent	Sunitinib Malate	Pfizer	marketed	Small molecule kinase inhibitor	Receptor tyrosine kinases (RTKs): PDGFRα, PDGFRβ, VEGFR1, VEGFR2, VEGFR3, KIT, FLT3, CSF-1R, RET	2006-01-01

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Anti-angiogenic agent class)

Bayer · 1 drug in this class
Vastra Gotaland Region · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Anti-VEGF injections — Competitive Intelligence Brief. https://druglandscape.com/ci/anti-vegf-injections. Accessed 2026-05-16.

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