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Anti-TNF Drug — Competitive Intelligence Brief
phase 2
TNF-alpha inhibitor
TNF-alpha
Immunology
Small molecule
Live · refreshed every 30 min
Target snapshot
Anti-TNF Drug (Anti-TNF Drug) — Schneider Children's Medical Center, Israel. Anti-TNF drugs block the action of tumor necrosis factor-alpha (TNF-alpha), a protein involved in systemic inflammation.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Anti-TNF Drug TARGET | Anti-TNF Drug | Schneider Children's Medical Center, Israel | phase 2 | TNF-alpha inhibitor | TNF-alpha | |
| Abrilada | Adalimumab-Afzb | AbbVie | marketed | TNF blocker | Tumor necrosis factor-alpha (TNF-alpha) | 2002-01-01 |
| Humira | ADALIMUMAB | AbbVie | marketed | TNF blocker | Tumor Necrosis Factor-alpha (TNF-alpha) | 2002-01-01 |
| etanercept or adalimumab | etanercept or adalimumab | University of Glasgow | marketed | TNF-alpha inhibitor | TNF-alpha (tumor necrosis factor-alpha) | |
| Infliximab-Dyyb | Infliximab-Dyyb | Asan Medical Center | marketed | TNF-alpha inhibitor; monoclonal antibody | TNF-alpha (TNFα) | |
| Etanercept + Methotrexate | Etanercept + Methotrexate | Wyeth is now a wholly owned subsidiary of Pfizer | marketed | TNF inhibitor + DMARD combination | TNF-alpha receptor (etanercept); dihydrofolate reductase (methotrexate) | |
| infliximab, etanercept, adalimumab | infliximab, etanercept, adalimumab | University Hospital, Strasbourg, France | marketed | TNF-alpha inhibitor | TNF-alpha (tumor necrosis factor-alpha) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (TNF-alpha inhibitor class)
- Abbott · 4 drugs in this class
- Centre for Human Drug Research, Netherlands · 2 drugs in this class
- Samsung Bioepis Co., Ltd. · 2 drugs in this class
- Alvotech Swiss AG · 2 drugs in this class
- UCB Pharma · 2 drugs in this class
- Celltrion · 2 drugs in this class
- AbbVie (prior sponsor, Abbott) · 2 drugs in this class
- Assistance Publique Hopitaux De Marseille · 1 drug in this class
- Asan Medical Center · 1 drug in this class
- Carmel Medical Center · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Anti-TNF Drug — Competitive Intelligence Brief. https://druglandscape.com/ci/anti-tnf-drug. Accessed 2026-05-18.
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