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antabuse (disulfiram) — Competitive Intelligence Brief
marketed
Aldehyde dehydrogenase inhibitor
Aldehyde dehydrogenase (ALDH)
Psychiatry / Addiction Medicine
Small molecule
Live · refreshed every 30 min
Target snapshot
antabuse (disulfiram) (antabuse (disulfiram)) — Psykiatrisk Center Gentofte. Disulfiram inhibits the enzyme aldehyde dehydrogenase, causing toxic acetaldehyde accumulation when alcohol is consumed, producing an aversive reaction that discourages drinking.
Comparator set (2 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| antabuse (disulfiram) TARGET | antabuse (disulfiram) | Psykiatrisk Center Gentofte | marketed | Aldehyde dehydrogenase inhibitor | Aldehyde dehydrogenase (ALDH) | |
| Antabuse | DISULFIRAM | marketed | Aldehyde Dehydrogenase Inhibitor [EPC] | Lysyl oxidase homolog 4 | 1951-01-01 | |
| disulfiram plus lorazepam | disulfiram plus lorazepam | University of New Mexico | marketed | Aldehyde dehydrogenase inhibitor plus benzodiazepine | Aldehyde dehydrogenase (ALDH); GABA-A receptor |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Aldehyde dehydrogenase inhibitor class)
- Psykiatrisk Center Gentofte · 1 drug in this class
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Cite this brief
Drug Landscape (2026). antabuse (disulfiram) — Competitive Intelligence Brief. https://druglandscape.com/ci/antabuse-disulfiram. Accessed 2026-05-16.
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