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AN2690 Topical Solution, 5% — Competitive Intelligence Brief

AN2690 Topical Solution, 5% (AN2690 Topical Solution, 5%) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Topical antifungal (squalene epoxidase inhibitor). Area: Dermatology / Infectious Disease.

phase 3 Topical antifungal (squalene epoxidase inhibitor) Squalene epoxidase Dermatology / Infectious Disease Small molecule Live · refreshed every 30 min

Target snapshot

AN2690 Topical Solution, 5% (AN2690 Topical Solution, 5%) — Pfizer. AN2690 is a topical antifungal that inhibits fungal squalene epoxidase, disrupting ergosterol synthesis in the fungal cell membrane.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
AN2690 Topical Solution, 5% TARGET AN2690 Topical Solution, 5% Pfizer phase 3 Topical antifungal (squalene epoxidase inhibitor) Squalene epoxidase
NAFT500 (pediatric) NAFT500 (pediatric) Merz North America, Inc. marketed Allylamine antifungal Squalene epoxidase
Tavaborole 5% Topical Solution Tavaborole 5% Topical Solution Pfizer marketed Benzoxaborole antifungal Squalene epoxidase
Terbinafine Tablets Terbinafine Tablets Oregon Health and Science University marketed Allylamine antifungal Squalene epoxidase
Jublia® Jublia® Dong-A ST Co., Ltd. marketed Azole antifungal Squalene epoxidase (fungal)
Lotrimin Ultra® Lotrimin Ultra® Sun Pharmaceutical Industries, Inc. marketed Allylamine antifungal Squalene epoxidase
NAFT600 (pediatric) NAFT600 (pediatric) Merz North America, Inc. marketed Topical antifungal (allylamine) Squalene epoxidase (fungal)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Topical antifungal (squalene epoxidase inhibitor) class)

  1. Pfizer · 1 drug in this class

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Cite this brief

Drug Landscape (2026). AN2690 Topical Solution, 5% — Competitive Intelligence Brief. https://druglandscape.com/ci/an2690-topical-solution-5. Accessed 2026-05-14.

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