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AN2690 Topical Solution, 5% — Competitive Intelligence Brief
phase 3
Topical antifungal (squalene epoxidase inhibitor)
Squalene epoxidase
Dermatology / Infectious Disease
Small molecule
Live · refreshed every 30 min
Target snapshot
AN2690 Topical Solution, 5% (AN2690 Topical Solution, 5%) — Pfizer. AN2690 is a topical antifungal that inhibits fungal squalene epoxidase, disrupting ergosterol synthesis in the fungal cell membrane.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| AN2690 Topical Solution, 5% TARGET | AN2690 Topical Solution, 5% | Pfizer | phase 3 | Topical antifungal (squalene epoxidase inhibitor) | Squalene epoxidase | |
| NAFT500 (pediatric) | NAFT500 (pediatric) | Merz North America, Inc. | marketed | Allylamine antifungal | Squalene epoxidase | |
| Tavaborole 5% Topical Solution | Tavaborole 5% Topical Solution | Pfizer | marketed | Benzoxaborole antifungal | Squalene epoxidase | |
| Terbinafine Tablets | Terbinafine Tablets | Oregon Health and Science University | marketed | Allylamine antifungal | Squalene epoxidase | |
| Jublia® | Jublia® | Dong-A ST Co., Ltd. | marketed | Azole antifungal | Squalene epoxidase (fungal) | |
| Lotrimin Ultra® | Lotrimin Ultra® | Sun Pharmaceutical Industries, Inc. | marketed | Allylamine antifungal | Squalene epoxidase | |
| NAFT600 (pediatric) | NAFT600 (pediatric) | Merz North America, Inc. | marketed | Topical antifungal (allylamine) | Squalene epoxidase (fungal) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Topical antifungal (squalene epoxidase inhibitor) class)
- Pfizer · 1 drug in this class
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Cite this brief
Drug Landscape (2026). AN2690 Topical Solution, 5% — Competitive Intelligence Brief. https://druglandscape.com/ci/an2690-topical-solution-5. Accessed 2026-05-14.
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