Last reviewed · How we verify
AMR101 — Competitive Intelligence Brief
phase 3
Omega-3 fatty acid
Hepatic triglyceride synthesis pathway
Cardiovascular
Small molecule
Live · refreshed every 30 min
Target snapshot
AMR101 (AMR101) — Massachusetts General Hospital. AMR101 is a high-purity eicosapentaenoic acid (EPA) that reduces triglycerides by inhibiting hepatic triglyceride synthesis and enhancing fatty acid oxidation.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| AMR101 TARGET | AMR101 | Massachusetts General Hospital | phase 3 | Omega-3 fatty acid | Hepatic triglyceride synthesis pathway | |
| Omacor® | Omacor® | Hospital Universitari Vall d'Hebron Research Institute | marketed | Omega-3 fatty acid | Hepatic triglyceride synthesis pathway | |
| Epanova | OMEGA-3-CARBOXYLIC ACIDS | AstraZeneca | marketed | Omega-3 Fatty Acid | 2014-01-01 | |
| LOVAZA Omega 3-acid ethyl esters | LOVAZA Omega 3-acid ethyl esters | University of Michigan | marketed | Omega-3 fatty acid supplement | ||
| Antara (fenofibrate) + Lovaza | Antara (fenofibrate) + Lovaza | GlaxoSmithKline | marketed | Fibrate + Omega-3 fatty acid combination | PPARα (fenofibrate); GPR120, GPR40 (omega-3 fatty acids) | |
| Product 3 - Standard Fish Oil Triglyceride | Product 3 - Standard Fish Oil Triglyceride | RDC Clinical Pty Ltd | marketed | Omega-3 fatty acid supplement | ||
| Omega-3-acid ethyl esters 90 | Omega-3-acid ethyl esters 90 | Pronova BioPharma | marketed | Fibrate-like lipid-lowering agent / Omega-3 fatty acid |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Omega-3 fatty acid class)
- Estudios Clínicos Latino América · 1 drug in this class
- Hospital Universitari Vall d'Hebron Research Institute · 1 drug in this class
- Massachusetts General Hospital · 1 drug in this class
- S.L.A. Pharma AG · 1 drug in this class
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Cite this brief
Drug Landscape (2026). AMR101 — Competitive Intelligence Brief. https://druglandscape.com/ci/amr101. Accessed 2026-05-13.
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