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Amphotericin B Deoxycholate — Competitive Intelligence Brief
marketed
Polyene antifungal
Ergosterol
Infectious Diseases
Small molecule
Live · refreshed every 30 min
Target snapshot
Amphotericin B Deoxycholate (Amphotericin B Deoxycholate) — Drugs for Neglected Diseases. Amphotericin B binds to ergosterol in fungal cell membranes, creating pores that disrupt membrane integrity and cause cell death.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Amphotericin B Deoxycholate TARGET | Amphotericin B Deoxycholate | Drugs for Neglected Diseases | marketed | Polyene antifungal | Ergosterol | |
| Mycostatin | nystatin | Generic (originally Squibb) | marketed | Polyene Antifungal [EPC] | Ergosterol (fungal cell membrane) | 1954-01-01 |
| Liposomal Amphotericin B | Liposomal Amphotericin B | Taiwan Liposome Company | marketed | Polyene antifungal | Ergosterol | |
| Loceryl NL + Cosmetic varnish | Loceryl NL + Cosmetic varnish | Galderma R&D | marketed | Morpholine antifungal | Δ14-steroid reductase and Δ8→Δ7-isomerase (ergosterol biosynthesis pathway) | |
| Nystatin 10000U/ml | Nystatin 10000U/ml | Riyadh Colleges of Dentistry and Pharmacy | marketed | Polyene macrolide antifungal | Ergosterol | |
| Nystatin oral suspension | Nystatin oral suspension | Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections | marketed | Polyene macrolide antifungal | Ergosterol | |
| Group 3: Liposomal amphotericin B | Group 3: Liposomal amphotericin B | Fundacion Nacional de Dermatologia | phase 3 | Polyene antifungal | Ergosterol |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Polyene antifungal class)
- Bharat Serums and Vaccines Limited · 1 drug in this class
- CSPC ZhongQi Pharmaceutical Technology Co., Ltd. · 1 drug in this class
- CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd. · 1 drug in this class
- Dr. Falk Pharma GmbH · 1 drug in this class
- Drugs for Neglected Diseases · 1 drug in this class
- Federal University of Health Science of Porto Alegre · 1 drug in this class
- Fundacion Nacional de Dermatologia · 1 drug in this class
- Pfizer · 1 drug in this class
- Poitiers University Hospital · 1 drug in this class
- Taiwan Liposome Company · 1 drug in this class
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- Amphotericin B Deoxycholate CI watch — RSS
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- Amphotericin B Deoxycholate alone — RSS
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Cite this brief
Drug Landscape (2026). Amphotericin B Deoxycholate — Competitive Intelligence Brief. https://druglandscape.com/ci/amphotericin-b-deoxycholate. Accessed 2026-05-13.
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