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Last reviewed 2026-06-10 · How we verify

Amitriptyline Oxide — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Amitriptyline Oxide (AMITRIPTYLINOXIDE) competitive landscape: 2 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Area: Oncology.

phase 3 Proto-oncogene tyrosine-protein kinase receptor Ret Oncology Small molecule Live · refreshed every 30 min

Target snapshot

Amitriptyline Oxide (AMITRIPTYLINOXIDE). Amitriptylinoxide works by binding to and inhibiting the proto-oncogene tyrosine-protein kinase receptor Ret.

Comparator set (2 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Amitriptyline Oxide TARGET	AMITRIPTYLINOXIDE		phase 3		Proto-oncogene tyrosine-protein kinase receptor Ret
Retevmo	SELPERCATINIB	Eli Lilly	marketed	Kinase Inhibitor [EPC]	Proto-oncogene tyrosine-protein kinase receptor Ret	2020-01-01
Lenvima	LENVATINIB	Eisai	marketed	Kinase Inhibitor [EPC]	Proto-oncogene tyrosine-protein kinase receptor Ret	2015-01-01

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape

No sponsor landscape data.

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Cite this brief

Drug Landscape (2026). Amitriptyline Oxide — Competitive Intelligence Brief. https://druglandscape.com/ci/amitriptylinoxide. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing