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Barhemsys — Competitive Intelligence Brief

Barhemsys (AMISULPRIDE) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Dopamine-2 Receptor Antagonist [EPC]. Area: Neuroscience.

marketed Dopamine-2 Receptor Antagonist [EPC] D(2) dopamine receptor Neuroscience Small molecule Live · refreshed every 30 min

Target snapshot

Barhemsys (AMISULPRIDE) — Acacia. Barhemsys works by blocking dopamine receptors in the brain.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Barhemsys TARGET AMISULPRIDE Acacia marketed Dopamine-2 Receptor Antagonist [EPC] D(2) dopamine receptor 2020-01-01
Pramipexole (Mirapex) Pramipexole (Mirapex) Massachusetts General Hospital marketed Dopamine agonist D2 dopamine receptor, D3 dopamine receptor
LYBALVI LYBALVI Alkermes, Inc. marketed Atypical antipsychotic with opioid antagonist D2 dopamine receptor, 5-HT7 serotonin receptor, mu-opioid receptor
Aripiprazole Augmentation Aripiprazole Augmentation Centre for Addiction and Mental Health marketed Atypical antipsychotic / dopamine partial agonist D2 dopamine receptor, 5-HT1A serotonin receptor
Quetiapine and Topiramate Quetiapine and Topiramate University of Cincinnati marketed Atypical antipsychotic + anticonvulsant mood stabilizer combination D2 dopamine receptor, 5-HT2A serotonin receptor (quetiapine); voltage-gated sodium channels, carbonic anhydrase (topiramate)
Adjunctive asenapine Adjunctive asenapine Lori Davis, MD marketed Atypical antipsychotic D2 dopamine receptor, 5-HT2A serotonin receptor
Asenapine - Double Blind Asenapine - Double Blind Organon and Co phase 3 Atypical antipsychotic D2 dopamine receptor, 5-HT2A serotonin receptor

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Dopamine-2 Receptor Antagonist [EPC] class)

  1. Acacia · 1 drug in this class
  2. Rising · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Barhemsys — Competitive Intelligence Brief. https://druglandscape.com/ci/amisulpride. Accessed 2026-05-13.

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