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amifostine trihydrate — Competitive Intelligence Brief

amifostine trihydrate (amifostine trihydrate) competitive landscape: 3 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Cytoprotective agent. Area: Oncology.

marketed Cytoprotective agent Oncology Small molecule Live · refreshed every 30 min

Target snapshot

amifostine trihydrate (amifostine trihydrate) — City of Hope Medical Center. Amifostine is a prodrug that is converted to an active free thiol compound, which acts as a cytoprotective and radioprotective agent by scavenging free radicals and reducing DNA damage.

Comparator set (3 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
amifostine trihydrate TARGET amifostine trihydrate City of Hope Medical Center marketed Cytoprotective agent
Zinecard DEXRAZOXANE Pfizer marketed Cytoprotective Agent DNA topoisomerase 2-alpha 1995-01-01
Blenoxane BLEOMYCIN Bristol-Myers Squibb marketed Cytoprotective Agent Aspartyl/asparaginyl beta-hydroxylase 1973-01-01
BNP7787 BNP7787 Alliance for Clinical Trials in Oncology phase 3 Cytoprotective agent / Cisplatin protectant Cisplatin (indirect; forms inactivating complex)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Cytoprotective agent class)

  1. City of Hope Medical Center · 1 drug in this class

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Cite this brief

Drug Landscape (2026). amifostine trihydrate — Competitive Intelligence Brief. https://druglandscape.com/ci/amifostine-trihydrate. Accessed 2026-05-14.

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