Last reviewed · How we verify
amifostine trihydrate — Competitive Intelligence Brief
marketed
Cytoprotective agent
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
amifostine trihydrate (amifostine trihydrate) — City of Hope Medical Center. Amifostine is a prodrug that is converted to an active free thiol compound, which acts as a cytoprotective and radioprotective agent by scavenging free radicals and reducing DNA damage.
Comparator set (3 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| amifostine trihydrate TARGET | amifostine trihydrate | City of Hope Medical Center | marketed | Cytoprotective agent | ||
| Zinecard | DEXRAZOXANE | Pfizer | marketed | Cytoprotective Agent | DNA topoisomerase 2-alpha | 1995-01-01 |
| Blenoxane | BLEOMYCIN | Bristol-Myers Squibb | marketed | Cytoprotective Agent | Aspartyl/asparaginyl beta-hydroxylase | 1973-01-01 |
| BNP7787 | BNP7787 | Alliance for Clinical Trials in Oncology | phase 3 | Cytoprotective agent / Cisplatin protectant | Cisplatin (indirect; forms inactivating complex) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Cytoprotective agent class)
- City of Hope Medical Center · 1 drug in this class
Subscribe to ongoing alerts
Push every new event for this competitive set into your RSS reader, IFTTT/Zapier workflow, or email digest:
- amifostine trihydrate CI watch — RSS
- amifostine trihydrate CI watch — Atom
- amifostine trihydrate CI watch — JSON
- amifostine trihydrate alone — RSS
- Whole Cytoprotective agent class — RSS
Cite this brief
Drug Landscape (2026). amifostine trihydrate — Competitive Intelligence Brief. https://druglandscape.com/ci/amifostine-trihydrate. Accessed 2026-05-14.
Build your own brief
Pick any drug + add comparators:
https://druglandscape.com/ci/{slug}— auto-detected competitorshttps://druglandscape.com/ci/{slug}?vs=drug1,drug2,drug3— explicit comparators- Brand names auto-resolve:
/ci/keytruda→ 301 →/ci/pembrolizumab