Who are Firdapse's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Guanidin, fampridine, Ezogabine/Retigabine IR, SR-fampridine, Sustained-release oral dalfampridine, ,4-diaminopyridine.

How often does this brief refresh?

Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

How do I get this as a recurring report?

Subscribe to /feed/ci/amifampridine.xml in any RSS reader (Feedly, Inoreader, NewsBlur). Every regulatory action, trial readout, or patent event lands in your feed automatically.

Last reviewed 2026-06-10 · How we verify

Firdapse — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Firdapse (AMIFAMPRIDINE) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Potassium Channel Blocker. Area: Neuroscience.

marketed Potassium Channel Blocker Voltage-gated potassium channel Neuroscience Small molecule Live · refreshed every 30 min

Target snapshot

Firdapse (AMIFAMPRIDINE) — Catalyst Pharms. Firdapse works by blocking potassium channels in the nervous system, allowing more nerve impulses to be transmitted.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Firdapse TARGET	AMIFAMPRIDINE	Catalyst Pharms	marketed	Potassium Channel Blocker	Voltage-gated potassium channel	2018-01-01
Guanidin	GUANIDINE	Merck & Co.	marketed	Acetylcholine Releasing Agent	Voltage-gated potassium channel	1939-01-01
fampridine	fampridine	Biogen	marketed		Voltage-gated potassium channel, Potassium voltage-gated channel subfamily C member 1, Potassium voltage-gated channel subfamily C member 2
Ezogabine/Retigabine IR	Ezogabine/Retigabine IR	GlaxoSmithKline	marketed	Potassium channel opener	Kv7 (KCNQ) voltage-gated potassium channels
SR-fampridine	SR-fampridine	University of Southern Denmark	marketed	Potassium channel blocker	Voltage-gated potassium channels
Sustained-release oral dalfampridine	Sustained-release oral dalfampridine	Sheba Medical Center	marketed	Potassium channel blocker	Voltage-gated potassium channels (Kv channels)
,4-diaminopyridine	,4-diaminopyridine	National Center for Research Resources (NCRR)	phase 3	Potassium channel blocker	Voltage-gated potassium channels (presynaptic)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Potassium Channel Blocker class)

Catalyst Pharms · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Firdapse — Competitive Intelligence Brief. https://druglandscape.com/ci/amifampridine. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing