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AMG 719 — Competitive Intelligence Brief
phase 2
Bispecific T-cell engager (BiTE)
CD3 and FLT3
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
AMG 719 (AMG 719) — Amgen. AMG 719 is a bispecific antibody that simultaneously engages CD3 on T cells and FLT3 on acute myeloid leukemia blasts to redirect immune killing.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| AMG 719 TARGET | AMG 719 | Amgen | phase 2 | Bispecific T-cell engager (BiTE) | CD3 and FLT3 | |
| Teclistamab (Tec) | Teclistamab (Tec) | University of Heidelberg Medical Center | marketed | Bispecific T-cell engager (BiTE) | CD3 and BCMA | |
| CHS-0214 | CHS-0214 | Coherus Oncology, Inc. | phase 3 | Bispecific T-cell engager (BiTE) | CD3 and tumor-associated antigen (specific target not publicly disclosed) | |
| IMA203 | IMA203 | Immatics US, Inc. | phase 3 | Bispecific T-cell engager (BiTE) | CD3 and PRAME | |
| AK111 | AK111 | Akeso | phase 3 | Bispecific T-cell engager (BiTE) | CD3 and EGFR | |
| Placebo+AK111 | Placebo+AK111 | Akeso | phase 3 | Bispecific T-cell engager (BiTE) | CD3 and tumor-associated antigen (specific target not publicly disclosed) | |
| ABP 798 | ABP 798 | Amgen | phase 3 | Bispecific T-cell engager (BiTE) | CD3 / PMEL (gp100) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Bispecific T-cell engager (BiTE) class)
- Akeso · 3 drugs in this class
- Amgen · 2 drugs in this class
- Arrevus Inc. · 1 drug in this class
- Coherus Oncology, Inc. · 1 drug in this class
- Immatics US, Inc. · 1 drug in this class
- University of Heidelberg Medical Center · 1 drug in this class
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Push every new event for this competitive set into your RSS reader, IFTTT/Zapier workflow, or email digest:
- AMG 719 CI watch — RSS
- AMG 719 CI watch — Atom
- AMG 719 CI watch — JSON
- AMG 719 alone — RSS
- Whole Bispecific T-cell engager (BiTE) class — RSS
Cite this brief
Drug Landscape (2026). AMG 719 — Competitive Intelligence Brief. https://druglandscape.com/ci/amg-719. Accessed 2026-05-14.
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