Who are AMG 531's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Promacta, Nplate, Revolade®, TPO, Doptelet Pill, TPO-RAs.

How often does this brief refresh?

Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-14 · How we verify

AMG 531 — Competitive Intelligence Brief

AMG 531 (AMG 531) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Thrombopoietin receptor agonist. Area: Hematology.

phase 3 Thrombopoietin receptor agonist TPO receptor (c-Mpl) Hematology Biologic Live · refreshed every 30 min

Target snapshot

AMG 531 (AMG 531) — Amgen. AMG 531 is a thrombopoietin (TPO) receptor agonist that stimulates platelet production by binding to and activating the TPO receptor on megakaryocytes.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
AMG 531 TARGET	AMG 531	Amgen	phase 3	Thrombopoietin receptor agonist	TPO receptor (c-Mpl)
Promacta	ELTROMBOPAG	Novartis	marketed	Thrombopoietin Receptor Agonist	Thrombopoietin receptor	2008-01-01
Nplate	ROMIPLOSTIM	Amgen	marketed	Thrombopoietin Receptor Agonist [EPC]	Thrombopoietin receptor	2008-01-01
Revolade®	Revolade®	Centro de Atencion e Investigacion Medica	marketed	Thrombopoietin receptor agonist	TPO receptor (TPOR/MPL)
TPO	TPO	Shenyang Sunshine Pharmaceutical Co., LTD.	marketed	Thrombopoietin receptor agonist	c-Mpl (thrombopoietin receptor)
Doptelet Pill	Doptelet Pill	Hvidovre University Hospital	marketed	Thrombopoietin receptor agonist	TPO receptor (TPOR/MPL)
TPO-RAs	TPO-RAs	Institute of Hematology & Blood Diseases Hospital, China	marketed	Thrombopoietin receptor agonist	TPO receptor (MPLS)

Recent regulatory actions (last 90 days)

2026-03-16 — Promacta · FDA · approved · US · Novartis

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Thrombopoietin receptor agonist class)

Centro de Atencion e Investigacion Medica · 2 drugs in this class
Institute of Hematology & Blood Diseases Hospital, China · 2 drugs in this class
Jiangsu HengRui Medicine Co., Ltd. · 2 drugs in this class
Hvidovre University Hospital · 1 drug in this class
Kyowa Kirin Korea Co., Ltd. · 1 drug in this class
Peking Union Medical College Hospital · 1 drug in this class
PharmaEssentia Japan K.K. · 1 drug in this class
Qilu Pharmaceutical Co., Ltd. · 1 drug in this class
Shenyang Sunshine Pharmaceutical Co., LTD. · 1 drug in this class
Amgen · 1 drug in this class

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Cite this brief

Drug Landscape (2026). AMG 531 — Competitive Intelligence Brief. https://druglandscape.com/ci/amg-531. Accessed 2026-05-14.

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