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Tezspire — Competitive Intelligence Brief
marketed
Thymic Stromal Lymphopoietin Blocker [EPC]
Thymic stromal lymphopoietin
Respiratory
Biologic
Live · refreshed every 30 min
Target snapshot
Tezspire (AMG 157) — AstraZeneca. Tezspire blocks the action of Thymic Stromal Lymphopoietin (TSLP), a protein that triggers inflammation in the airways.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Tezspire TARGET | AMG 157 | AstraZeneca | marketed | Thymic Stromal Lymphopoietin Blocker [EPC] | Thymic stromal lymphopoietin | 2021-01-01 |
| TEZSPIRE | TEZEPELUMAB-EKKO | ASTRAZENECA AB | marketed | Thymic Stromal Lymphopoietin Blocker [EPC] | Thymic stromal lymphopoietin | |
| Tezspire | Tezspire | Qilu Pharmaceutical Co., Ltd. | marketed | Thymic stromal lymphopoietin | ||
| tezepelumab (Arm1&Arm2) | tezepelumab (Arm1&Arm2) | Qilu Pharmaceutical Co., Ltd. | phase 3 | Monoclonal antibody | Thymic stromal lymphopoietin (TSLP) | |
| Experimental: Tezepelumab | Experimental: Tezepelumab | AstraZeneca | phase 3 | Monoclonal antibody; TSLP inhibitor | TSLP (Thymic Stromal Lymphopoietin) | |
| Biological: Experimental: Tezepelumab | Biological: Experimental: Tezepelumab | AstraZeneca | phase 3 | TSLP antagonist monoclonal antibody | TSLP (Thymic Stromal Lymphopoietin) | |
| Tezspire | TEZEPELUMAB | AstraZeneca / Amgen | marketed | Thymic Stromal Lymphopoietin Blocker [EPC] | 2021-01-01 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Thymic Stromal Lymphopoietin Blocker [EPC] class)
- ASTRAZENECA AB · 1 drug in this class
- AstraZeneca · 1 drug in this class
- AstraZeneca / Amgen · 1 drug in this class
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- Tezspire CI watch — RSS
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- Whole Thymic Stromal Lymphopoietin Blocker [EPC] class — RSS
Cite this brief
Drug Landscape (2026). Tezspire — Competitive Intelligence Brief. https://druglandscape.com/ci/amg-157. Accessed 2026-05-13.
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