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Tezspire — Competitive Intelligence Brief

Tezspire (AMG 157) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Thymic Stromal Lymphopoietin Blocker [EPC]. Area: Respiratory.

marketed Thymic Stromal Lymphopoietin Blocker [EPC] Thymic stromal lymphopoietin Respiratory Biologic Live · refreshed every 30 min

Target snapshot

Tezspire (AMG 157) — AstraZeneca. Tezspire blocks the action of Thymic Stromal Lymphopoietin (TSLP), a protein that triggers inflammation in the airways.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Tezspire TARGET AMG 157 AstraZeneca marketed Thymic Stromal Lymphopoietin Blocker [EPC] Thymic stromal lymphopoietin 2021-01-01
TEZSPIRE TEZEPELUMAB-EKKO ASTRAZENECA AB marketed Thymic Stromal Lymphopoietin Blocker [EPC] Thymic stromal lymphopoietin
Tezspire Tezspire Qilu Pharmaceutical Co., Ltd. marketed Thymic stromal lymphopoietin
tezepelumab (Arm1&Arm2) tezepelumab (Arm1&Arm2) Qilu Pharmaceutical Co., Ltd. phase 3 Monoclonal antibody Thymic stromal lymphopoietin (TSLP)
Experimental: Tezepelumab Experimental: Tezepelumab AstraZeneca phase 3 Monoclonal antibody; TSLP inhibitor TSLP (Thymic Stromal Lymphopoietin)
Biological: Experimental: Tezepelumab Biological: Experimental: Tezepelumab AstraZeneca phase 3 TSLP antagonist monoclonal antibody TSLP (Thymic Stromal Lymphopoietin)
Tezspire TEZEPELUMAB AstraZeneca / Amgen marketed Thymic Stromal Lymphopoietin Blocker [EPC] 2021-01-01

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Thymic Stromal Lymphopoietin Blocker [EPC] class)

  1. ASTRAZENECA AB · 1 drug in this class
  2. AstraZeneca · 1 drug in this class
  3. AstraZeneca / Amgen · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Tezspire — Competitive Intelligence Brief. https://druglandscape.com/ci/amg-157. Accessed 2026-05-13.

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