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ALXN2220 — Competitive Intelligence Brief
phase 3
Monoclonal antibody
Phosphatidylserine
Neurology
Small molecule
Live · refreshed every 30 min
Target snapshot
ALXN2220 (ALXN2220) — Neurimmune AG. ALXN2220 is a monoclonal antibody that targets phosphatidylserine on apoptotic cells to enhance their clearance and reduce neuroinflammation.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| ALXN2220 TARGET | ALXN2220 | Neurimmune AG | phase 3 | Monoclonal antibody | Phosphatidylserine | |
| [89Zr]Zr-crefmirlimab berdoxam | 89zr-zr-crefmirlimab-berdoxam | Pfizer | marketed | Radiolabeled Monoclonal Antibody | Fibroblast Activation Protein (FAP) | Not specified |
| Venetoclax; Rituximab | venetoclax-rituximab | Pfizer | marketed | BCL-2 inhibitor (venetoclax); Monoclonal antibody (rituximab) | BCL-2 (venetoclax); CD20 (rituximab) | N/A |
| Hympavzi | MARSTACIMAB | Pfizer Inc | marketed | Monoclonal Antibody | Factor Xa | 2025-01-01 |
| Beyfortus | NIRSEVIMAB | AstraZeneca | marketed | Respiratory Syncytial Virus Anti-F Protein Monoclonal Antibody [EPC] | RSV | 2023-01-01 |
| Darzalex | daratumumab | Johnson & Johnson | marketed | Monoclonal antibody | CD38 | 2015-01-01 |
| Praxbind | IDARUCIZUMAB | Boehringer Ingelheim | marketed | Humanized Monoclonal Antibody Fragment [EPC] | dabigatran and its acylglucuronide metabolites | 2015-01-01 |
Recent regulatory actions (last 90 days)
- — Beyfortus · FDA · approved · US · AstraZeneca
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Monoclonal antibody class)
- Pfizer · 7 drugs in this class
- argenx · 7 drugs in this class
- Johnson & Johnson · 2 drugs in this class
- German CLL Study Group · 2 drugs in this class
- Amgen · 2 drugs in this class
- Hoffmann-La Roche · 2 drugs in this class
- Brii Biosciences Limited · 2 drugs in this class
- Alexion Pharmaceuticals, Inc. · 2 drugs in this class
- Biotest · 2 drugs in this class
- Fondazione Italiana Linfomi - ETS · 2 drugs in this class
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- ALXN2220 CI watch — RSS
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- ALXN2220 CI watch — JSON
- ALXN2220 alone — RSS
- Whole Monoclonal antibody class — RSS
Cite this brief
Drug Landscape (2026). ALXN2220 — Competitive Intelligence Brief. https://druglandscape.com/ci/alxn2220. Accessed 2026-05-15.
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