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Alogliptin and glyburide — Competitive Intelligence Brief
phase 3
DPP-4 inhibitor + sulfonylurea combination
DPP-4 (dipeptidyl peptidase-4) and sulfonylurea receptor (SUR1)
Diabetes
Small molecule
Live · refreshed every 30 min
Target snapshot
Alogliptin and glyburide (Alogliptin and glyburide) — Takeda. Alogliptin inhibits dipeptidyl peptidase-4 (DPP-4) to increase incretin levels and lower blood glucose, while glyburide stimulates pancreatic beta cells to release insulin.
Comparator set (2 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Alogliptin and glyburide TARGET | Alogliptin and glyburide | Takeda | phase 3 | DPP-4 inhibitor + sulfonylurea combination | DPP-4 (dipeptidyl peptidase-4) and sulfonylurea receptor (SUR1) | |
| Teneligliptin + Sulfonylurea | Teneligliptin + Sulfonylurea | Tanabe Pharma Corporation | phase 3 | DPP-4 inhibitor + Sulfonylurea combination | DPP-4 enzyme; ATP-sensitive potassium channels on pancreatic beta cells | |
| Gemigliptin/Glimepiride combination | Gemigliptin/Glimepiride combination | LG Life Sciences | phase 3 | DPP-4 inhibitor + sulfonylurea combination | DPP-4 (dipeptidyl peptidase-4) and sulfonylurea receptor (SUR1) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (DPP-4 inhibitor + sulfonylurea combination class)
- LG Life Sciences · 1 drug in this class
- Takeda · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Alogliptin and glyburide — Competitive Intelligence Brief. https://druglandscape.com/ci/alogliptin-and-glyburide. Accessed 2026-05-16.
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