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ALKS 8700 — Competitive Intelligence Brief
phase 3
Antipsychotic combination (long-acting injectable)
Dopamine D2 receptor
Psychiatry/Neurology
Small molecule
Live · refreshed every 30 min
Target snapshot
ALKS 8700 (ALKS 8700) — Biogen. ALKS 8700 is a combination of aripiprazole monohydrate and flupenthixol decanoate designed to provide sustained antipsychotic activity through dopamine modulation.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| ALKS 8700 TARGET | ALKS 8700 | Biogen | phase 3 | Antipsychotic combination (long-acting injectable) | Dopamine D2 receptor | |
| Risperidone high dose | Risperidone high dose | Johnson & Johnson Pharmaceutical Research & Development, L.L.C. | marketed | Atypical antipsychotic | Dopamine D2 receptor; Serotonin 5-HT2A receptor | |
| Quetiapine 600mg | Quetiapine 600mg | AstraZeneca | marketed | atypical antipsychotic | ["serotonin 5-HT2A receptors", "dopamine D2 receptors"] | |
| olanzapine + fluoxetine | olanzapine + fluoxetine | University of Florida | marketed | Atypical antipsychotic + SSRI combination | Dopamine D2 receptor, serotonin 5-HT2A receptor, serotonin transporter (SERT) | |
| aripiprazole (Abilify) | aripiprazole (Abilify) | Massachusetts General Hospital | marketed | Atypical antipsychotic | Dopamine D2 receptor (partial agonist), Serotonin 5-HT1A receptor (partial agonist) | |
| Valium + Akineton + Dehydrobenzperidol + Atropine sulfate | Valium + Akineton + Dehydrobenzperidol + Atropine sulfate | Universitaire Ziekenhuizen KU Leuven | marketed | Combination sedative-antipsychotic | GABA-A receptor, dopamine D2 receptor, muscarinic acetylcholine receptor | |
| Cabergoline (Dopamine Agonist) | Cabergoline (Dopamine Agonist) | University Hospital, Basel, Switzerland | marketed | Dopamine agonist | Dopamine D2 receptor |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Antipsychotic combination (long-acting injectable) class)
- Biogen · 1 drug in this class
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Cite this brief
Drug Landscape (2026). ALKS 8700 — Competitive Intelligence Brief. https://druglandscape.com/ci/alks-8700. Accessed 2026-05-13.
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