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ALGLUCOSIDASE ALFA (MYOZYME) — Competitive Intelligence Brief
marketed
Enzyme replacement therapy
Acid alpha-glucosidase (GAA)
Rare genetic disease / Metabolic disorder
Small molecule
Live · refreshed every 30 min
Target snapshot
ALGLUCOSIDASE ALFA (MYOZYME) (ALGLUCOSIDASE ALFA (MYOZYME)) — Genzyme, a Sanofi Company. Alglucosidase alfa is a recombinant human acid alpha-glucosidase enzyme that breaks down glycogen accumulated in lysosomes, restoring normal cellular function in Pompe disease.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| ALGLUCOSIDASE ALFA (MYOZYME) TARGET | ALGLUCOSIDASE ALFA (MYOZYME) | Genzyme, a Sanofi Company | marketed | Enzyme replacement therapy | Acid alpha-glucosidase (GAA) | |
| creon 35.000 Ph.U (R) | creon 35.000 Ph.U (R) | Hospital Clinico Universitario de Santiago | marketed | Pancreatic enzyme replacement therapy | ||
| Panzytrat 25.000 FIP-E units of Lipase | Panzytrat 25.000 FIP-E units of Lipase | Foundation for Liver Research | marketed | Pancreatic enzyme replacement therapy | Triglycerides and dietary lipids | |
| RDD to Palynziq | RDD to Palynziq | BioMarin Pharmaceutical | marketed | Enzyme replacement therapy | Phenylalanine ammonia-lyase (PAL) | |
| Pancrelipase Capsules | Pancrelipase Capsules | Ohio State University | marketed | Pancreatic enzyme replacement therapy | ||
| Cerezyme® | Cerezyme® | ISU Abxis Co., Ltd. | marketed | Enzyme replacement therapy | Glucocerebrosidase (β-glucosidase) | |
| Myozyme® (alglucosidase alfa) | Myozyme® (alglucosidase alfa) | Genzyme, a Sanofi Company | marketed | Enzyme replacement therapy | Acid alpha-glucosidase (GAA); lysosomal glycogen |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Enzyme replacement therapy class)
- BioMarin Pharmaceutical · 5 drugs in this class
- Sanofi · 3 drugs in this class
- JCR Pharmaceuticals Co., Ltd. · 2 drugs in this class
- Genzyme, a Sanofi Company · 2 drugs in this class
- Pfizer Inc. · 1 drug in this class
- Shire · 1 drug in this class
- Alexion Pharmaceuticals, Inc. · 1 drug in this class
- University of Missouri-Columbia · 1 drug in this class
- Eurofarma Laboratorios S.A. · 1 drug in this class
- ISU Abxis Co., Ltd. · 1 drug in this class
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Cite this brief
Drug Landscape (2026). ALGLUCOSIDASE ALFA (MYOZYME) — Competitive Intelligence Brief. https://druglandscape.com/ci/alglucosidase-alfa-myozyme. Accessed 2026-05-18.
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