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Alendronate (ALN) — Competitive Intelligence Brief

Alendronate (ALN) (Alendronate (ALN)) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Bisphosphonate. Area: Bone metabolism / Rheumatology.

marketed Bisphosphonate Farnesyl pyrophosphate synthase (FPPS); hydroxyapatite Bone metabolism / Rheumatology Small molecule Live · refreshed every 30 min

Target snapshot

Alendronate (ALN) (Alendronate (ALN)) — Chinese University of Hong Kong. Alendronate inhibits osteoclast-mediated bone resorption by binding to hydroxyapatite on the bone surface and blocking farnesyl pyrophosphate synthase in the mevalonate pathway.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Alendronate (ALN) TARGET Alendronate (ALN) Chinese University of Hong Kong marketed Bisphosphonate Farnesyl pyrophosphate synthase (FPPS); hydroxyapatite
Boniva IBANDRONIC ACID Hoffmann La Roche marketed Bisphosphonate Farnesyl pyrophosphate synthase 2003-01-01
Skelid TILUDRONIC ACID marketed Bisphosphonate 72 kDa type IV collagenase 1997-01-01
Aredia PAMIDRONIC ACID marketed Bisphosphonate Farnesyl pyrophosphate synthase 1991-01-01
Didronel ETIDRONIC ACID Procter And Gamble marketed Bisphosphonate 1977-01-01
Placebo to zoledronic acid Placebo to zoledronic acid Amgen marketed Bisphosphonate Farnesyl pyrophosphate synthase; hydroxyapatite in bone
Alendronate (Fosamax) Alendronate (Fosamax) Medical University of South Carolina marketed Bisphosphonate Farnesyl pyrophosphate synthase (FPPS); hydroxyapatite binding

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Bisphosphonate class)

  1. · 2 drugs in this class
  2. Amgen · 2 drugs in this class
  3. National Taiwan University Hospital · 2 drugs in this class
  4. Sanofi · 2 drugs in this class
  5. Ludwig-Maximilians - University of Munich · 2 drugs in this class
  6. Chinese University of Hong Kong · 1 drug in this class
  7. Chinese Society of Lung Cancer · 1 drug in this class
  8. Aarhus University Hospital · 1 drug in this class
  9. Eisai Inc. · 1 drug in this class
  10. Daiichi Sankyo Co., Ltd. · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Alendronate (ALN) — Competitive Intelligence Brief. https://druglandscape.com/ci/alendronate-aln. Accessed 2026-06-10.

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