Who are Aldara 5% Topical Cream's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Aldara (imiquimod) cream, 5%, Aldara Cream 5%, Imiquimod 5% Topical Cream, Imiquimod 5% Cream, Imiquimod 3.75% Cream, standard dose of HCQ.

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Last reviewed 2026-05-17 · How we verify

Aldara 5% Topical Cream — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Aldara 5% Topical Cream (Aldara 5% Topical Cream) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Toll-like receptor 7 (TLR7) agonist. Area: Dermatology/Oncology.

phase 3 Toll-like receptor 7 (TLR7) agonist TLR7 Dermatology/Oncology Small molecule Live · refreshed every 30 min

Target snapshot

Aldara 5% Topical Cream (Aldara 5% Topical Cream) — University Medical Centre Maribor. Imiquimod is a toll-like receptor 7 (TLR7) agonist that activates innate immune responses to treat skin lesions.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
Aldara 5% Topical Cream TARGET	Aldara 5% Topical Cream	University Medical Centre Maribor	phase 3	Toll-like receptor 7 (TLR7) agonist	TLR7
Aldara (imiquimod) cream, 5%	Aldara (imiquimod) cream, 5%	Graceway Pharmaceuticals, LLC	marketed	TLR7 agonist	TLR7 (Toll-like receptor 7)
Aldara Cream 5%	Aldara Cream 5%	Hordinsky, Maria K., MD	marketed	Toll-like receptor 7 (TLR7) agonist	TLR7
Imiquimod 5% Topical Cream	Imiquimod 5% Topical Cream	University of Michigan	marketed	Toll-like receptor 7 (TLR7) agonist	TLR7
Imiquimod 5% Cream	Imiquimod 5% Cream	Massachusetts General Hospital	marketed	TLR7 agonist / Immune response modifier	TLR7 (Toll-like receptor 7)
Imiquimod 3.75% Cream	Imiquimod 3.75% Cream	Medical University of Graz	marketed	TLR7 agonist	TLR7 (Toll-like receptor 7)
standard dose of HCQ	standard dose of HCQ	University of Sao Paulo General Hospital	marketed	Antimalarial immunosuppressant	Toll-like receptors (TLR7, TLR9); phospholipase C

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Toll-like receptor 7 (TLR7) agonist class)

Hordinsky, Maria K., MD · 1 drug in this class
University Medical Centre Maribor · 1 drug in this class
University of Michigan · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Aldara 5% Topical Cream — Competitive Intelligence Brief. https://druglandscape.com/ci/aldara-5-topical-cream. Accessed 2026-05-17.

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