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Aldactone — Competitive Intelligence Brief
marketed
Potassium-sparing diuretic, aldosterone antagonist
Aldosterone receptors at aldosterone-dependent sodium-potassium exchange site in distal convoluted renal tubule
Metabolic
Small molecule
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Target snapshot
Aldactone (Spironolactone) — Pfizer Inc.. Aldosterone antagonist causing increased sodium and water excretion while retaining potassium.
Comparator set
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Aldactone TARGET | Spironolactone | Pfizer Inc. | marketed | Potassium-sparing diuretic, aldosterone antagonist | Aldosterone receptors at aldosterone-dependent sodium-potassium exchange site in distal convoluted renal tubule |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Potassium-sparing diuretic, aldosterone antagonist class)
- Pfizer Inc. · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Aldactone — Competitive Intelligence Brief. https://druglandscape.com/ci/aldactone. Accessed 2026-05-14.
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