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Albumin-bound Paclitaxel plus S-1 — Competitive Intelligence Brief
phase 3
Combination chemotherapy (taxane + fluoropyrimidine)
Microtubules (paclitaxel); Thymidylate synthase (S-1)
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
Albumin-bound Paclitaxel plus S-1 (Albumin-bound Paclitaxel plus S-1) — Huazhong University of Science and Technology. Albumin-bound paclitaxel inhibits microtubule depolymerization to arrest cell cycle, while S-1 (tegafur/gimeracil/oteracil) inhibits thymidylate synthase to disrupt DNA synthesis, together providing synergistic cytotoxic effects.
Comparator set (1 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Albumin-bound Paclitaxel plus S-1 TARGET | Albumin-bound Paclitaxel plus S-1 | Huazhong University of Science and Technology | phase 3 | Combination chemotherapy (taxane + fluoropyrimidine) | Microtubules (paclitaxel); Thymidylate synthase (S-1) | |
| Taxane plus Intermittent Capecitabine | Taxane plus Intermittent Capecitabine | Sun Yat-sen University | phase 3 | Combination chemotherapy (taxane + fluoropyrimidine) | Microtubules (taxane); thymidylate synthase (capecitabine/5-FU) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Combination chemotherapy (taxane + fluoropyrimidine) class)
- Huazhong University of Science and Technology · 1 drug in this class
- Sun Yat-sen University · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Albumin-bound Paclitaxel plus S-1 — Competitive Intelligence Brief. https://druglandscape.com/ci/albumin-bound-paclitaxel-plus-s-1. Accessed 2026-05-17.
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