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AL8326 tablets — Competitive Intelligence Brief
phase 3
Histone deacetylase (HDAC) inhibitor
Histone deacetylase (HDAC)
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
AL8326 tablets (AL8326 tablets) — Advenchen Laboratories Nanjing Ltd.. AL8326 is a selective inhibitor of histone deacetylase (HDAC) that promotes acetylation of histones and non-histone proteins to alter gene expression and induce anti-tumor effects.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| AL8326 tablets TARGET | AL8326 tablets | Advenchen Laboratories Nanjing Ltd. | phase 3 | Histone deacetylase (HDAC) inhibitor | Histone deacetylase (HDAC) | |
| Vorinostat (VOR) | Vorinostat (VOR) | University of North Carolina, Chapel Hill | marketed | Histone deacetylase (HDAC) inhibitor | Histone deacetylases (HDAC1, HDAC2, HDAC3, HDAC6, HDAC8) | |
| Low dose valproate | Low dose valproate | Mario Negri Institute for Pharmacological Research | marketed | Histone deacetylase (HDAC) inhibitor | Histone deacetylases (HDACs) | |
| SPARC0912 | SPARC0912 | Sun Pharma Advanced Research Company Limited | phase 3 | Histone deacetylase (HDAC) inhibitor | Histone deacetylase (HDAC) | |
| HIP2101 | HIP2101 | Hanmi Pharmaceutical Company Limited | phase 3 | Histone deacetylase (HDAC) inhibitor | Histone deacetylase (HDAC) | |
| Belinostat Injection | Belinostat Injection | Acrotech Biopharma Inc. | phase 3 | Histone deacetylase (HDAC) inhibitor | Histone deacetylase (HDAC) | |
| MC0518 | MC0518 | medac GmbH | phase 3 | Histone deacetylase (HDAC) inhibitor | Histone deacetylase (HDAC) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Histone deacetylase (HDAC) inhibitor class)
- Acrotech Biopharma Inc. · 1 drug in this class
- Advenchen Laboratories Nanjing Ltd. · 1 drug in this class
- BeBetter Med Inc · 1 drug in this class
- Hanmi Pharmaceutical Company Limited · 1 drug in this class
- Mario Negri Institute for Pharmacological Research · 1 drug in this class
- Sun Pharma Advanced Research Company Limited · 1 drug in this class
- University of North Carolina, Chapel Hill · 1 drug in this class
- medac GmbH · 1 drug in this class
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Cite this brief
Drug Landscape (2026). AL8326 tablets — Competitive Intelligence Brief. https://druglandscape.com/ci/al8326-tablets. Accessed 2026-05-13.
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