Who are AK112 with SCRT and CapeOX's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Nivolumab + Relatlimab, TAR-210, BAT2206, Nivolumab-relatlimab FDC, AK112, Gemcitabine, Cisplatin, AK112, Carboplatin, Paxlitaxel.

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Last reviewed 2026-05-17 · How we verify

AK112 with SCRT and CapeOX — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

AK112 with SCRT and CapeOX (AK112 with SCRT and CapeOX) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Bispecific monoclonal antibody (PD-1/LAG-3 inhibitor). Area: Oncology.

phase 2 Bispecific monoclonal antibody (PD-1/LAG-3 inhibitor) PD-1 and LAG-3 Oncology Small molecule Live · refreshed every 30 min

Target snapshot

AK112 with SCRT and CapeOX (AK112 with SCRT and CapeOX) — fan li. AK112 is a bispecific antibody that simultaneously engages PD-1 and LAG-3 to enhance anti-tumor immune responses, combined with chemotherapy (capecitabine and oxaliplatin) to treat solid tumors.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
AK112 with SCRT and CapeOX TARGET	AK112 with SCRT and CapeOX	fan li	phase 2	Bispecific monoclonal antibody (PD-1/LAG-3 inhibitor)	PD-1 and LAG-3
Nivolumab + Relatlimab	Nivolumab + Relatlimab	H. Lee Moffitt Cancer Center and Research Institute	marketed	Dual checkpoint inhibitor (PD-1 and LAG-3 inhibitor combination)	PD-1 and LAG-3
TAR-210	TAR-210	Janssen Research & Development, LLC	phase 3	Bispecific antibody	PD-1 and LAG-3
BAT2206	BAT2206	Bio-Thera Solutions	phase 3	Bispecific antibody; dual checkpoint inhibitor	Likely PD-1 and LAG-3 (or similar dual checkpoint targets)
Nivolumab-relatlimab FDC	Nivolumab-relatlimab FDC	Bristol-Myers Squibb	phase 3	Dual checkpoint inhibitor (PD-1/LAG-3)	PD-1 and LAG-3
AK112, Gemcitabine, Cisplatin	AK112, Gemcitabine, Cisplatin	Akeso	phase 3	Bispecific antibody (PD-1/LAG-3 inhibitor) combined with chemotherapy	PD-1 and LAG-3
AK112, Carboplatin, Paxlitaxel	AK112, Carboplatin, Paxlitaxel	Akeso	phase 3	Bispecific antibody (PD-1/LAG-3 inhibitor) + chemotherapy combination	PD-1 and LAG-3

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Bispecific monoclonal antibody (PD-1/LAG-3 inhibitor) class)

fan li · 1 drug in this class

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Cite this brief

Drug Landscape (2026). AK112 with SCRT and CapeOX — Competitive Intelligence Brief. https://druglandscape.com/ci/ak112-with-scrt-and-capeox. Accessed 2026-05-17.

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