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AK112, Gemcitabine, Cisplatin — Competitive Intelligence Brief

AK112, Gemcitabine, Cisplatin (AK112, Gemcitabine, Cisplatin) competitive landscape: 5 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Bispecific antibody (PD-1/LAG-3 inhibitor) combined with chemotherapy. Area: Oncology.

phase 3 Bispecific antibody (PD-1/LAG-3 inhibitor) combined with chemotherapy PD-1 and LAG-3 Oncology Small molecule Live · refreshed every 30 min

Target snapshot

AK112, Gemcitabine, Cisplatin (AK112, Gemcitabine, Cisplatin) — Akeso. AK112 is a bispecific antibody that simultaneously engages PD-1 and LAG-3 to enhance anti-tumor immune responses, while gemcitabine and cisplatin are chemotherapy agents that damage tumor DNA.

Comparator set (5 drugs)

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DrugGenericSponsorPhaseClassTargetApproval / PDUFA
AK112, Gemcitabine, Cisplatin TARGET AK112, Gemcitabine, Cisplatin Akeso phase 3 Bispecific antibody (PD-1/LAG-3 inhibitor) combined with chemotherapy PD-1 and LAG-3
Nivolumab + Relatlimab Nivolumab + Relatlimab H. Lee Moffitt Cancer Center and Research Institute marketed Dual checkpoint inhibitor (PD-1 and LAG-3 inhibitor combination) PD-1 and LAG-3
AK112, Carboplatin, Paxlitaxel AK112, Carboplatin, Paxlitaxel Akeso phase 3 Bispecific antibody (PD-1/LAG-3 inhibitor) + chemotherapy combination PD-1 and LAG-3
BAT2206 BAT2206 Bio-Thera Solutions phase 3 Bispecific antibody; dual checkpoint inhibitor Likely PD-1 and LAG-3 (or similar dual checkpoint targets)
TAR-210 TAR-210 Janssen Research & Development, LLC phase 3 Bispecific antibody PD-1 and LAG-3
Nivolumab-relatlimab FDC Nivolumab-relatlimab FDC Bristol-Myers Squibb phase 3 Dual checkpoint inhibitor (PD-1/LAG-3) PD-1 and LAG-3

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Bispecific antibody (PD-1/LAG-3 inhibitor) combined with chemotherapy class)

  1. Akeso · 1 drug in this class

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Cite this brief

Drug Landscape (2026). AK112, Gemcitabine, Cisplatin — Competitive Intelligence Brief. https://druglandscape.com/ci/ak112-gemcitabine-cisplatin. Accessed 2026-05-18.

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