Who are AK111's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Teclistamab (Tec), Placebo+AK111, CHS-0214, AK101, IMA203, ABP 798.

How often does this brief refresh?

Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-13 · How we verify

AK111 — Competitive Intelligence Brief

AK111 (AK111) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Bispecific T-cell engager (BiTE). Area: Oncology.

phase 3 Bispecific T-cell engager (BiTE) CD3 and EGFR Oncology Biologic Live · refreshed every 30 min

Target snapshot

AK111 (AK111) — Akeso. AK111 is a bispecific antibody that simultaneously engages CD3 on T cells and EGFR on tumor cells to redirect immune attack against EGFR-expressing cancers.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target
AK111 TARGET	AK111	Akeso	phase 3	Bispecific T-cell engager (BiTE)	CD3 and EGFR
Teclistamab (Tec)	Teclistamab (Tec)	University of Heidelberg Medical Center	marketed	Bispecific T-cell engager (BiTE)	CD3 and BCMA
Placebo+AK111	Placebo+AK111	Akeso	phase 3	Bispecific T-cell engager (BiTE)	CD3 and tumor-associated antigen (specific target not publicly disclosed)
CHS-0214	CHS-0214	Coherus Oncology, Inc.	phase 3	Bispecific T-cell engager (BiTE)	CD3 and tumor-associated antigen (specific target not publicly disclosed)
AK101	AK101	Akeso	phase 3	Bispecific T-cell engager (BiTE)	CD3 / PSMA
IMA203	IMA203	Immatics US, Inc.	phase 3	Bispecific T-cell engager (BiTE)	CD3 and PRAME
ABP 798	ABP 798	Amgen	phase 3	Bispecific T-cell engager (BiTE)	CD3 / PMEL (gp100)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Bispecific T-cell engager (BiTE) class)

Akeso · 3 drugs in this class
Amgen · 2 drugs in this class
Arrevus Inc. · 1 drug in this class
Coherus Oncology, Inc. · 1 drug in this class
Immatics US, Inc. · 1 drug in this class
University of Heidelberg Medical Center · 1 drug in this class

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Cite this brief

Drug Landscape (2026). AK111 — Competitive Intelligence Brief. https://druglandscape.com/ci/ak111. Accessed 2026-05-13.

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