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aglatimagene besadenovec + valacyclovir — Competitive Intelligence Brief
phase 3
Oncolytic immunotherapy
IL-12 expression; adenovirus replication machinery
Oncology
Biologic
Live · refreshed every 30 min
Target snapshot
aglatimagene besadenovec + valacyclovir (aglatimagene besadenovec + valacyclovir) — Candel Therapeutics, Inc.. Aglatimagene besadenovec is an oncolytic adenovirus expressing IL-12 that replicates in tumor cells and triggers immune activation, combined with valacyclovir (an antiviral) to modulate viral replication kinetics.
Comparator set (1 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| aglatimagene besadenovec + valacyclovir TARGET | aglatimagene besadenovec + valacyclovir | Candel Therapeutics, Inc. | phase 3 | Oncolytic immunotherapy | IL-12 expression; adenovirus replication machinery | |
| Zopapogene imadenovec (Zopa) | Zopapogene imadenovec (Zopa) | Precigen, Inc | marketed | Oncolytic immunotherapy | Tumor cells (non-selective replication); immunostimulatory transgene product |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Oncolytic immunotherapy class)
- Candel Therapeutics, Inc. · 1 drug in this class
- Precigen, Inc · 1 drug in this class
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Cite this brief
Drug Landscape (2026). aglatimagene besadenovec + valacyclovir — Competitive Intelligence Brief. https://druglandscape.com/ci/aglatimagene-besadenovec-valacyclovir. Accessed 2026-05-16.
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