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AFM 13 — Competitive Intelligence Brief
phase 1
bispecific antibody
CD30, CD16A
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
AFM 13 (AFM 13) — Affimed GmbH. AFM 13 is a tetravalent bispecific antibody construct that targets CD30 on tumor cells and CD16A on natural killer (NK) cells, enhancing NK cell-mediated cytotoxicity against CD30-positive tumors.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| AFM 13 TARGET | AFM 13 | Affimed GmbH | phase 1 | bispecific antibody | CD30, CD16A | |
| Elrexfio | Elranatamab | Pfizer | marketed | Bispecific antibody | BCMA (B-cell maturation antigen) on plasma cells, plasmablasts, and multiple myeloma cells; CD3 on T-cells | 2023-01-01 |
| Elrexfio | elranatamab | Pfizer | marketed | Bispecific antibody | BCMA (B-cell maturation antigen) on plasma cells, plasmablasts, and multiple myeloma cells; CD3 on T-cells | 2023-01-01 |
| Elrantamab | elrantamab | Pfizer | marketed | Bispecific Antibody | BCMA (B-cell maturation antigen) | |
| CHS-1420 | CHS-1420 | Coherus Oncology, Inc. | phase 3 | Bispecific antibody | CD47 and CD40 | |
| BAT1406 | BAT1406 | Bio-Thera Solutions | phase 3 | Bispecific antibody; PD-1/TGF-β inhibitor | PD-1 and TGF-β | |
| L19IL2 + L19TNF | L19IL2 + L19TNF | Philogen S.p.A. | phase 3 | Bispecific antibody-cytokine fusion | Fibronectin extra domain B (EDB); IL-2 receptor; TNF receptor |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (bispecific antibody class)
- Affimed GmbH · 1 drug in this class
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Cite this brief
Drug Landscape (2026). AFM 13 — Competitive Intelligence Brief. https://druglandscape.com/ci/afm-13. Accessed 2026-05-13.
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