Who are Afatinib treatment's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Rybrevant, NERATINIB, Inlyta, REGORAFENIB, PONATINIB HYDROCHLORIDE, PAZOPANIB.

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Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-16 · How we verify

Afatinib treatment — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Afatinib treatment (Afatinib treatment) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: EGFR inhibitor. Area: Oncology.

phase 2 EGFR inhibitor EGFR Oncology Small molecule Live · refreshed every 30 min

Target snapshot

Afatinib treatment (Afatinib treatment) — Sheba Medical Center. Epidermal growth factor receptor (EGFR) inhibitor

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Afatinib treatment TARGET	Afatinib treatment	Sheba Medical Center	phase 2	EGFR inhibitor	EGFR
Rybrevant	AMIVANTAMAB	Johnson & Johnson	marketed		EGFR, MET	2021-01-01
NERATINIB	NERATINIB		marketed		EGFR, HER2, HER4	2017-01-01
Inlyta	Axitinib	Pfizer	marketed	Receptor tyrosine kinase inhibitor	Vascular endothelial growth factor receptors (VEGFR)-1, VEGFR-2, VEGFR-3	2012-01-01
REGORAFENIB	REGORAFENIB		marketed		RET, VEGFR1, VEGFR2, VEGFR3, KIT, PDGFR-alpha, PDGFR-beta, FGFR1, FGFR2, TIE2, DDR2, TrkA, Eph2A, RAF-1, BRAF, BRAF V600E, SAPK2, PTK5, Abl, CSF1R	2012-01-01
PONATINIB HYDROCHLORIDE	PONATINIB HYDROCHLORIDE		marketed		ABL, T315I mutant ABL, VEGFR, PDGFR, FGFR, EPH receptors, SRC family, KIT, RET, TIE2, FLT3	2012-01-01
PAZOPANIB	PAZOPANIB		marketed	Kinase Inhibitor [EPC]	VEGFR-1, VEGFR-2, VEGFR-3, PDGFR-ɑ, PDGFR-β, FGFR-1, FGFR-3, Kit, Itk, Lck, c-Fms	2009-01-01

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (EGFR inhibitor class)

Arbeitsgemeinschaft medikamentoese Tumortherapie · 1 drug in this class
Association pour la Recherche sur le Temps Biologique et la Chronothérapie · 1 drug in this class
Guangdong Association of Clinical Trials · 1 drug in this class
Hoffmann-La Roche · 1 drug in this class
Janssen Research & Development, LLC · 1 drug in this class
Shanghai Henlius Biotech · 1 drug in this class
Sheba Medical Center · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Afatinib treatment — Competitive Intelligence Brief. https://druglandscape.com/ci/afatinib-treatment. Accessed 2026-05-16.

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