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Adjuvant FOLFOX — Competitive Intelligence Brief
phase 2
Platinum-based chemotherapeutic agent and thymidylate synthase inhibitor
DNA
Oncology
Small molecule
Live · refreshed every 30 min
Target snapshot
Adjuvant FOLFOX (Adjuvant FOLFOX) — Asan Medical Center. Oxaliplatin and 5-fluorouracil inhibit DNA replication and transcription by cross-linking DNA and interfering with thymidylate synthase.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Adjuvant FOLFOX TARGET | Adjuvant FOLFOX | Asan Medical Center | phase 2 | Platinum-based chemotherapeutic agent and thymidylate synthase inhibitor | DNA | |
| CEDAZURIDINE | CEDAZURIDINE | marketed | Nucleoside Metabolic Inhibitor [EPC] | DNA methyltransferase | 2020-01-01 | |
| Dacogen | decitabine | Sun Pharma | marketed | Nucleoside Metabolic Inhibitor [EPC] | DNA (cytosine-5)-methyltransferase 1 | 2006-01-01 |
| Vidaza | azacitidine | Bristol-Myers Squibb | marketed | Nucleoside Metabolic Inhibitor [EPC] | DNA (cytosine-5)-methyltransferase 1 | 2004-01-01 |
| Zymar | GATIFLOXACIN | Allergan | marketed | DNA gyrase, DNA gyrase, DNA gyrase subunit A | 2003-01-01 | |
| Eloxatin | Oxaliplatin | Yakult Honsha | marketed | Platinum-based chemotherapy agent | DNA | 2002-01-01 |
| Hepsera | ADEFOVIR DIPIVOXIL | Gilead Sciences | marketed | Hepatitis B Virus Nucleoside Analog Reverse Transcriptase Inhibitor | DNA polymerase subunit gamma-1 | 2002-01-01 |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
- — Vidaza · 12053482 · Method of Use · US
- — Vidaza · 11571436 · Formulation · US
- — Vidaza · 8846628 · Formulation · US
Sponsor landscape (Platinum-based chemotherapeutic agent and thymidylate synthase inhibitor class)
- Asan Medical Center · 1 drug in this class
- Sun Yat-sen University · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Adjuvant FOLFOX — Competitive Intelligence Brief. https://druglandscape.com/ci/adjuvant-folfox. Accessed 2026-06-09.
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