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Adjunctive Zonisamide — Competitive Intelligence Brief

Adjunctive Zonisamide (Adjunctive Zonisamide) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Anticonvulsant / Antiepileptic drug. Area: Neurology.

marketed Anticonvulsant / Antiepileptic drug Voltage-gated sodium channels, T-type calcium channels, carbonic anhydrase Neurology Small molecule Live · refreshed every 30 min

Target snapshot

Adjunctive Zonisamide (Adjunctive Zonisamide) — Eisai Inc.. Zonisamide is an anticonvulsant that reduces neuronal excitability through multiple mechanisms including sodium and calcium channel blockade and carbonic anhydrase inhibition.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Adjunctive Zonisamide TARGET Adjunctive Zonisamide Eisai Inc. marketed Anticonvulsant / Antiepileptic drug Voltage-gated sodium channels, T-type calcium channels, carbonic anhydrase
Low dose zonisamide Low dose zonisamide Mario Negri Institute for Pharmacological Research marketed Anticonvulsant / Antiepileptic agent Voltage-gated sodium channels, T-type calcium channels, carbonic anhydrase
Oral Zonisamide Therapy Oral Zonisamide Therapy Affiliated Hospital of Nantong University marketed Anticonvulsant / Antiepileptic drug Voltage-gated sodium channels, T-type calcium channels, carbonic anhydrase
Placebo ZNS Placebo ZNS Impax Laboratories, LLC phase 3 Anticonvulsant / Antiepileptic agent Voltage-gated sodium channels, T-type calcium channels, carbonic anhydrase
Low dose carbamazepine Low dose carbamazepine Mario Negri Institute for Pharmacological Research marketed Anticonvulsant / Antiepileptic drug Voltage-gated sodium channels
Standard dose lamotrigine Standard dose lamotrigine Mario Negri Institute for Pharmacological Research marketed Anticonvulsant / Antiepileptic drug Voltage-gated sodium channels; glutamate release inhibition
Lamotrigine (drug) Lamotrigine (drug) MaineHealth marketed Anticonvulsant / Antiepileptic drug Voltage-gated sodium channels; glutamate release inhibition

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Anticonvulsant / Antiepileptic drug class)

  1. Mario Negri Institute for Pharmacological Research · 3 drugs in this class
  2. Eisai Inc. · 2 drugs in this class
  3. Affiliated Hospital of Nantong University · 1 drug in this class
  4. GlaxoSmithKline · 1 drug in this class
  5. MaineHealth · 1 drug in this class
  6. UCB Pharma · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Adjunctive Zonisamide — Competitive Intelligence Brief. https://druglandscape.com/ci/adjunctive-zonisamide. Accessed 2026-05-15.

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