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Adjunctive Zonisamide — Competitive Intelligence Brief
marketed
Anticonvulsant / Antiepileptic drug
Voltage-gated sodium channels, T-type calcium channels, carbonic anhydrase
Neurology
Small molecule
Live · refreshed every 30 min
Target snapshot
Adjunctive Zonisamide (Adjunctive Zonisamide) — Eisai Inc.. Zonisamide is an anticonvulsant that reduces neuronal excitability through multiple mechanisms including sodium and calcium channel blockade and carbonic anhydrase inhibition.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| Adjunctive Zonisamide TARGET | Adjunctive Zonisamide | Eisai Inc. | marketed | Anticonvulsant / Antiepileptic drug | Voltage-gated sodium channels, T-type calcium channels, carbonic anhydrase | |
| Low dose zonisamide | Low dose zonisamide | Mario Negri Institute for Pharmacological Research | marketed | Anticonvulsant / Antiepileptic agent | Voltage-gated sodium channels, T-type calcium channels, carbonic anhydrase | |
| Oral Zonisamide Therapy | Oral Zonisamide Therapy | Affiliated Hospital of Nantong University | marketed | Anticonvulsant / Antiepileptic drug | Voltage-gated sodium channels, T-type calcium channels, carbonic anhydrase | |
| Placebo ZNS | Placebo ZNS | Impax Laboratories, LLC | phase 3 | Anticonvulsant / Antiepileptic agent | Voltage-gated sodium channels, T-type calcium channels, carbonic anhydrase | |
| Low dose carbamazepine | Low dose carbamazepine | Mario Negri Institute for Pharmacological Research | marketed | Anticonvulsant / Antiepileptic drug | Voltage-gated sodium channels | |
| Standard dose lamotrigine | Standard dose lamotrigine | Mario Negri Institute for Pharmacological Research | marketed | Anticonvulsant / Antiepileptic drug | Voltage-gated sodium channels; glutamate release inhibition | |
| Lamotrigine (drug) | Lamotrigine (drug) | MaineHealth | marketed | Anticonvulsant / Antiepileptic drug | Voltage-gated sodium channels; glutamate release inhibition |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Anticonvulsant / Antiepileptic drug class)
- Mario Negri Institute for Pharmacological Research · 3 drugs in this class
- Eisai Inc. · 2 drugs in this class
- Affiliated Hospital of Nantong University · 1 drug in this class
- GlaxoSmithKline · 1 drug in this class
- MaineHealth · 1 drug in this class
- UCB Pharma · 1 drug in this class
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Cite this brief
Drug Landscape (2026). Adjunctive Zonisamide — Competitive Intelligence Brief. https://druglandscape.com/ci/adjunctive-zonisamide. Accessed 2026-05-15.
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