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Adjunct brexpiprazole — Competitive Intelligence Brief

Adjunct brexpiprazole (Adjunct brexpiprazole) competitive landscape: 5 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Serotonin-dopamine activity modulator (SDAM). Area: Psychiatry.

phase 3 Serotonin-dopamine activity modulator (SDAM) Dopamine D2 receptor, Serotonin 5-HT1A receptor Psychiatry Small molecule Live · refreshed every 30 min

Target snapshot

Adjunct brexpiprazole (Adjunct brexpiprazole) — H. Lundbeck A/S. Brexpiprazole is a serotonin-dopamine activity modulator (SDAM) that acts as a partial agonist at dopamine D2 and serotonin 5-HT1A receptors, used as an adjunctive treatment to enhance antidepressant efficacy.

Comparator set (5 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
Adjunct brexpiprazole TARGET Adjunct brexpiprazole H. Lundbeck A/S phase 3 Serotonin-dopamine activity modulator (SDAM) Dopamine D2 receptor, Serotonin 5-HT1A receptor
Abilify MyCite® Abilify MyCite® Otsuka Pharmaceutical Development & Commercialization, Inc. marketed Atypical antipsychotic with digital adherence monitoring Dopamine D2 receptor, serotonin 5-HT1A receptor
Aripiprazole (Fixed dose) Aripiprazole (Fixed dose) Otsuka Pharmaceutical Co., Ltd. phase 3 Atypical antipsychotic Dopamine D2 receptor, Serotonin 5-HT1A receptor
Brexpiprazole +ADT Brexpiprazole +ADT Otsuka Pharmaceutical Development & Commercialization, Inc. phase 3 Atypical antipsychotic (dopamine D2 partial agonist) Dopamine D2 receptor, Serotonin 5-HT1A receptor
Brexpiprazole (OPC-34712) Brexpiprazole (OPC-34712) Otsuka Pharmaceutical Development & Commercialization, Inc. phase 3 Atypical antipsychotic; serotonin-dopamine activity modulator (SDAM) Dopamine D2 receptor (partial agonist); serotonin 5-HT1A receptor (partial agonist); serotonin 5-HT2A receptor (antagonist)
OPC-34712FUM/ Brexpiprazole fumarate OPC-34712FUM/ Brexpiprazole fumarate Otsuka Pharmaceutical Co., Ltd. phase 3 Serotonin-dopamine activity modulator (SDAM); atypical antipsychotic Dopamine D2 receptor (partial agonist), serotonin 5-HT1A receptor (partial agonist), serotonin 5-HT2A receptor (antagonist)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Serotonin-dopamine activity modulator (SDAM) class)

  1. H. Lundbeck A/S · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Adjunct brexpiprazole — Competitive Intelligence Brief. https://druglandscape.com/ci/adjunct-brexpiprazole. Accessed 2026-05-14.

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