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AD109 dose1- A — Competitive Intelligence Brief
phase 2
orexin receptor antagonist
orexin receptor
Neurology
Small molecule
Live · refreshed every 30 min
Target snapshot
AD109 dose1- A (AD109 dose1- A) — Apnimed. AD109 is a small molecule that targets the orexin receptor to treat narcolepsy.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| AD109 dose1- A TARGET | AD109 dose1- A | Apnimed | phase 2 | orexin receptor antagonist | orexin receptor | |
| Quviviq | DARIDOREXANT | Idorsia | marketed | Orexin Receptor Antagonist [EPC] | Orexin receptor type 1 | 2022-01-01 |
| Dayvigo | LEMBOREXANT | Eisai | marketed | Orexin Receptor Antagonist [EPC] | Orexin receptor type 2 | 2019-01-01 |
| Suvorexant (Belsomra) | Suvorexant (Belsomra) | Massachusetts General Hospital | marketed | Orexin receptor antagonist | Orexin receptor 1 (OX1R) and Orexin receptor 2 (OX2R) | |
| Dose-matched Placebo to Suvorexant | Dose-matched Placebo to Suvorexant | Merck Sharp & Dohme LLC | phase 3 | Orexin receptor antagonist | OX1R and OX2R (orexin receptors) | |
| Suvorexant High Dose (HD) | Suvorexant High Dose (HD) | Merck Sharp & Dohme LLC | phase 3 | Orexin receptor antagonist | OX1R and OX2R (orexin receptors 1 and 2) | |
| Suvorexant Low Dose (LD) | Suvorexant Low Dose (LD) | Merck Sharp & Dohme LLC | phase 3 | Orexin receptor antagonist | OX1R and OX2R (orexin receptors 1 and 2) |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (orexin receptor antagonist class)
- Apnimed · 4 drugs in this class
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Cite this brief
Drug Landscape (2026). AD109 dose1- A — Competitive Intelligence Brief. https://druglandscape.com/ci/ad109-dose1-a. Accessed 2026-06-10.
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