Who are Actinium Ac 225-DOTA-Daratumumab's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Darzalex Faspro, Darzalex, Daratumumab and corticosteroid treatment, Darzalex, SCT800 and Daratumumab, SARCLISA.

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Last reviewed 2026-05-16 · How we verify

Actinium Ac 225-DOTA-Daratumumab — Competitive Intelligence Brief

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Actinium Ac 225-DOTA-Daratumumab (Actinium Ac 225-DOTA-Daratumumab) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: CD38-targeting radioligand therapy. Area: Oncology.

phase 1 CD38-targeting radioligand therapy CD38 Oncology Biologic Live · refreshed every 30 min

Target snapshot

Actinium Ac 225-DOTA-Daratumumab (Actinium Ac 225-DOTA-Daratumumab) — City of Hope Medical Center. Targeting CD38 with a radioligand

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Actinium Ac 225-DOTA-Daratumumab TARGET	Actinium Ac 225-DOTA-Daratumumab	City of Hope Medical Center	phase 1	CD38-targeting radioligand therapy	CD38
Darzalex Faspro	daratumumab-and-hyaluronidase-fihj	Pfizer	marketed	CD38-directed Cytolytic Antibody [EPC]	CD38	2020-01-01
Darzalex	daratumumab	Johnson & Johnson	marketed	Monoclonal antibody	CD38	2015-01-01
Daratumumab and corticosteroid treatment	Daratumumab and corticosteroid treatment	Institute of Hematology & Blood Diseases Hospital, China	marketed	Monoclonal antibody (CD38-targeting) combined with corticosteroid	CD38
Darzalex	Darzalex	Shanghai Henlius Biotech	marketed		Lymphocyte differentiation antigen CD38
SCT800 and Daratumumab	SCT800 and Daratumumab	Institute of Hematology & Blood Diseases Hospital, China	marketed	Bispecific T-cell engager (SCT800); CD38-targeting monoclonal antibody (Daratumumab)	CD19 and CD3 (SCT800); CD38 (Daratumumab)
SARCLISA	ISATUXIMAB-IRFC	SANOFI AVENTIS US	marketed	CD38-directed Cytolytic Antibody [EPC]	Lymphocyte differentiation antigen CD38

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (CD38-targeting radioligand therapy class)

City of Hope Medical Center · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Actinium Ac 225-DOTA-Daratumumab — Competitive Intelligence Brief. https://druglandscape.com/ci/actinium-ac-225-dota-daratumumab. Accessed 2026-05-16.

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