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ACT-539313 — Competitive Intelligence Brief

ACT-539313 (ACT-539313) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Dopamine D2 receptor antagonist. Area: Psychiatry.

phase 2 Dopamine D2 receptor antagonist D2 receptor Psychiatry Small molecule Live · refreshed every 30 min

Target snapshot

ACT-539313 (ACT-539313) — Idorsia Pharmaceuticals Ltd.. ACT-539313 is a selective dopamine D2 receptor antagonist.

Comparator set (6 drugs)

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DrugGenericSponsorPhaseClassTargetApproval / PDUFA
ACT-539313 TARGET ACT-539313 Idorsia Pharmaceuticals Ltd. phase 2 Dopamine D2 receptor antagonist D2 receptor
Risperidone tablets Risperidone tablets Sumitomo Pharma (Suzhou) Co., Ltd. marketed Atypical antipsychotic Dopamine D2 receptor; Serotonin 5-HT2A receptor
Risperidone, Haloperidol Risperidone, Haloperidol Ludwig-Maximilians - University of Munich marketed Antipsychotic Dopamine D2 receptor, Serotonin 5-HT2A receptor
Risperdal Consta Risperdal Consta Zogenix, Inc. marketed Atypical antipsychotic Dopamine D2 receptor, Serotonin 5-HT2A receptor
Risperidone, divalproex Risperidone, divalproex Nathan Kline Institute for Psychiatric Research marketed Atypical antipsychotic + anticonvulsant mood stabilizer combination Dopamine D2 receptor (risperidone); histone deacetylase / GABA pathway (divalproex)
Risperidone Long Acting Risperidone Long Acting Dartmouth-Hitchcock Medical Center marketed Atypical antipsychotic Dopamine D2 receptor, Serotonin 5-HT2A receptor
Aripiprazole or other oral antipsychotics Aripiprazole or other oral antipsychotics Otsuka Pharmaceutical Development & Commercialization, Inc. marketed Atypical antipsychotic Dopamine D2 receptor (partial agonist); Serotonin 5-HT1A receptor (agonist)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Dopamine D2 receptor antagonist class)

  1. Assistance Publique - Hôpitaux de Paris · 1 drug in this class
  2. Idorsia Pharmaceuticals Ltd. · 1 drug in this class
  3. Otsuka Pharmaceutical Co., Ltd. · 1 drug in this class

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Cite this brief

Drug Landscape (2026). ACT-539313 — Competitive Intelligence Brief. https://druglandscape.com/ci/act-539313. Accessed 2026-05-13.

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