Who are Acetadote's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Antizol, Cyanokit, Activated Charcoal, multivitamin, Actidose Aqua, Atropine/Neostigmine.

How often does this brief refresh?

Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-14 · How we verify

Acetadote — Competitive Intelligence Brief

Acetadote (Acetylcysteine) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Antidote. Area: Metabolic.

marketed Antidote Glutathione levels; reactive metabolite of acetaminophen Metabolic Small molecule Live · refreshed every 30 min

Target snapshot

Acetadote (Acetylcysteine) — Bristol-Myers Squibb. Acetylcysteine reduces liver injury from acetaminophen overdose by maintaining glutathione levels or providing alternate conjugation substrate.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Acetadote TARGET	Acetylcysteine	Bristol-Myers Squibb	marketed	Antidote	Glutathione levels; reactive metabolite of acetaminophen	1963-01-01
Antizol	FOMEPIZOLE	Par Pharm Inc	marketed	Antidote [EPC]	Alcohol dehydrogenase	1997-01-01
Cyanokit	HYDROXOCOBALAMIN	Btg Intl	marketed	Antidote		1978-01-01
Activated Charcoal	Activated Charcoal	State University of New York - Upstate Medical University	marketed	Adsorbent antidote
multivitamin	multivitamin	New York State Institute for Basic Research	marketed	Antidote [EPC]
Actidose Aqua	Actidose Aqua	National Institute of Allergy and Infectious Diseases (NIAID)	marketed	Adsorbent antidote
Atropine/Neostigmine	Atropine/Neostigmine	Hadassah Medical Organization	marketed	Antidote combination; anticholinergic + cholinesterase inhibitor	Muscarinic acetylcholine receptors (atropine); acetylcholinesterase (neostigmine)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

2026-05-21 — Acetadote · 8148356 · Formulation · US
2031-07-21 — Acetadote · 9327028 · Method of Use · US
2032-04-06 — Acetadote · 8722738 · Method of Use · US
2032-05-08 — Acetadote · 8747894 · Formulation · US
2032-05-08 — Acetadote · 9561204 · Method of Use · US
2032-05-08 — Acetadote · 9427421 · Formulation · US

Sponsor landscape (Antidote class)

· 1 drug in this class
Bristol-Myers Squibb · 1 drug in this class
Btg Intl · 1 drug in this class
National Cancer Institute, Naples · 1 drug in this class
Xijing Hospital of Digestive Diseases · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Acetadote — Competitive Intelligence Brief. https://druglandscape.com/ci/acetylcysteine. Accessed 2026-05-14.

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