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ABT-493 — Competitive Intelligence Brief

ABT-493 (ABT-493) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: protease inhibitor. Area: Infectious Diseases.

phase 2 protease inhibitor NS3/4A protease Infectious Diseases Small molecule Live · refreshed every 30 min

Target snapshot

ABT-493 (ABT-493) — AbbVie. ABT-493 is a protease inhibitor.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

DrugGenericSponsorPhaseClassTargetApproval / PDUFA
ABT-493 TARGET ABT-493 AbbVie phase 2 protease inhibitor NS3/4A protease
EXVIERA EXVIERA HaEmek Medical Center, Israel marketed Direct-acting antiviral (DAA) combination HCV NS5A, NS5B, NS3/4A protease
Post-transplant Grazoprevir and Elbasvir Post-transplant Grazoprevir and Elbasvir University of Maryland, Baltimore marketed Direct-acting antiviral (DAA) combination HCV NS3/4A protease and NS5A protein
OBV/PTV/r and DSV OBV/PTV/r and DSV Hannover Medical School marketed Direct-acting antiviral (DAA) combination HCV NS5A, NS3/4A protease, NS5B polymerase
PTV/r/OBV/DSV PTV/r/OBV/DSV National Taiwan University Hospital marketed HCV direct-acting antiviral combination HCV NS3/4A protease, NS5A, NS5B polymerase
glecaprevir/pibrentasvir tablets glecaprevir/pibrentasvir tablets Raymond T. Chung, MD marketed Direct-acting antiviral combination (NS3/4A protease inhibitor + NS5A inhibitor) HCV NS3/4A protease and NS5A protein
Zepatier plus Sofosbuvir Zepatier plus Sofosbuvir Massachusetts General Hospital marketed Direct-acting antiviral (DAA) combination HCV NS5A, NS3/4A protease, NS5B RNA polymerase

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (protease inhibitor class)

  1. Tibotec Pharmaceuticals, Ireland · 3 drugs in this class
  2. AbbVie · 1 drug in this class
  3. AbbVie (prior sponsor, Abbott) · 1 drug in this class
  4. R-Pharm · 1 drug in this class
  5. Tanabe Pharma Corporation · 1 drug in this class

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Cite this brief

Drug Landscape (2026). ABT-493 — Competitive Intelligence Brief. https://druglandscape.com/ci/abt-493. Accessed 2026-06-10.

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Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing