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ABT-493 — Competitive Intelligence Brief
phase 2
protease inhibitor
NS3/4A protease
Infectious Diseases
Small molecule
Live · refreshed every 30 min
Target snapshot
ABT-493 (ABT-493) — AbbVie. ABT-493 is a protease inhibitor.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| ABT-493 TARGET | ABT-493 | AbbVie | phase 2 | protease inhibitor | NS3/4A protease | |
| EXVIERA | EXVIERA | HaEmek Medical Center, Israel | marketed | Direct-acting antiviral (DAA) combination | HCV NS5A, NS5B, NS3/4A protease | |
| Post-transplant Grazoprevir and Elbasvir | Post-transplant Grazoprevir and Elbasvir | University of Maryland, Baltimore | marketed | Direct-acting antiviral (DAA) combination | HCV NS3/4A protease and NS5A protein | |
| OBV/PTV/r and DSV | OBV/PTV/r and DSV | Hannover Medical School | marketed | Direct-acting antiviral (DAA) combination | HCV NS5A, NS3/4A protease, NS5B polymerase | |
| PTV/r/OBV/DSV | PTV/r/OBV/DSV | National Taiwan University Hospital | marketed | HCV direct-acting antiviral combination | HCV NS3/4A protease, NS5A, NS5B polymerase | |
| glecaprevir/pibrentasvir tablets | glecaprevir/pibrentasvir tablets | Raymond T. Chung, MD | marketed | Direct-acting antiviral combination (NS3/4A protease inhibitor + NS5A inhibitor) | HCV NS3/4A protease and NS5A protein | |
| Zepatier plus Sofosbuvir | Zepatier plus Sofosbuvir | Massachusetts General Hospital | marketed | Direct-acting antiviral (DAA) combination | HCV NS5A, NS3/4A protease, NS5B RNA polymerase |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (protease inhibitor class)
- Tibotec Pharmaceuticals, Ireland · 3 drugs in this class
- AbbVie · 1 drug in this class
- AbbVie (prior sponsor, Abbott) · 1 drug in this class
- R-Pharm · 1 drug in this class
- Tanabe Pharma Corporation · 1 drug in this class
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Cite this brief
Drug Landscape (2026). ABT-493 — Competitive Intelligence Brief. https://druglandscape.com/ci/abt-493. Accessed 2026-06-10.
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