Who are Verzenio's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Hernexeos, Wayrilz, Itovebi, Romvimza, LAZERTINIB, Itovebi.

How often does this brief refresh?

Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-13 · How we verify

Verzenio — Competitive Intelligence Brief

Verzenio (abemaciclib) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Kinase inhibitor. Area: Oncology.

marketed Kinase inhibitor Cyclin-dependent kinases 4 and 6 (CDK4/CDK6) Oncology Live · refreshed every 30 min

Target snapshot

Verzenio (abemaciclib) — Eli Lilly. Abemaciclib inhibits CDK4 and CDK6, blocking Rb phosphorylation and G1/S cell cycle progression.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
Verzenio TARGET	abemaciclib	Eli Lilly	marketed	Kinase inhibitor	Cyclin-dependent kinases 4 and 6 (CDK4/CDK6)	2017-01-01
Hernexeos	ZONGERTINIB	Boehringer Ingelheim	marketed	Kinase Inhibitor [EPC]		2025-01-01
Wayrilz	RILZABRUTINIB	Genzyme Corp	marketed	Kinase Inhibitor [EPC]		2025-01-01
Itovebi	INAVOLISIB	Genentech Inc	marketed	Kinase Inhibitor [EPC]		2025-01-01
Romvimza	VIMSELTINIB	Deciphera Pharms	marketed	Kinase Inhibitor [EPC]		2025-01-01
LAZERTINIB	LAZERTINIB		marketed	Kinase Inhibitor [EPC]		2024-01-01
Itovebi	inavolisib	Pfizer	marketed	Kinase Inhibitor [EPC]	phosphatidylinositol 3-kinase (PI3K) alpha (PIK3CA)	2024-01-01

Recent regulatory actions (last 90 days)

2026-02-26 — Hernexeos · FDA · approved · US · Boehringer Ingelheim

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Kinase inhibitor class)

Beijing Pearl Biotechnology Limited Liability Company · 1 drug in this class
Eli Lilly · 1 drug in this class
Pfizer · 1 drug in this class

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Cite this brief

Drug Landscape (2026). Verzenio — Competitive Intelligence Brief. https://druglandscape.com/ci/abemaciclib. Accessed 2026-05-13.

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