Who are ABBV-453's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Brukinsa, Calquence, Acalabrutinib capsule, (G) BQ-L14, MGd, Ibrutinib (Induction).

How often does this brief refresh?

Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Last reviewed 2026-05-13 · How we verify

ABBV-453 — Competitive Intelligence Brief

ABBV-453 (ABBV-453) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: BTK inhibitor. Area: Oncology.

phase 1 BTK inhibitor BTK Oncology Small molecule Live · refreshed every 30 min

Target snapshot

ABBV-453 (ABBV-453) — AbbVie. BTK inhibitor

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
ABBV-453 TARGET	ABBV-453	AbbVie	phase 1	BTK inhibitor	BTK
Brukinsa	BGB-3111	Beigene Usa Inc	marketed	Kinase Inhibitor [EPC]	Tyrosine-protein kinase BTK	2019-01-01
Calquence	ACALABRUTINIB	AstraZeneca	marketed	Kinase Inhibitor [EPC]	Tyrosine-protein kinase BTK	2017-01-01
Acalabrutinib capsule	Acalabrutinib capsule	AstraZeneca	marketed	Bruton's tyrosine kinase (BTK) inhibitor	BTK (Bruton's tyrosine kinase)
(G) BQ-L14	(G) BQ-L14	National Taiwan University Hospital	marketed	BTK inhibitor	BTK
MGd	MGd	Pharmacyclics LLC.	marketed	Bruton's tyrosine kinase (BTK) inhibitor	BTK (Bruton's tyrosine kinase)
Ibrutinib (Induction)	Ibrutinib (Induction)	Prof. Dr. M. Dreyling (co-chairman)	phase 3	Bruton's tyrosine kinase (BTK) inhibitor	BTK (Bruton's tyrosine kinase)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

2034-04-22 — Brukinsa · 10570139 · US
2034-04-22 — Brukinsa · 11142528 · US
2034-04-22 — Brukinsa · 9447106 · US
2037-08-15 — Brukinsa · 11591340 · US
2037-08-15 — Brukinsa · 10927117 · US

Sponsor landscape (BTK inhibitor class)

Acerta Pharma BV · 4 drugs in this class
AstraZeneca · 4 drugs in this class
AbbVie · 2 drugs in this class
Eli Lilly and Company · 1 drug in this class
Fuji Yakuhin Co., Ltd. · 1 drug in this class
Genzyme, a Sanofi Company · 1 drug in this class
GlaxoSmithKline · 1 drug in this class
Janssen Research & Development, LLC · 1 drug in this class
National Taiwan University Hospital · 1 drug in this class
Pfizer · 1 drug in this class

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Cite this brief

Drug Landscape (2026). ABBV-453 — Competitive Intelligence Brief. https://druglandscape.com/ci/abbv-453. Accessed 2026-05-13.

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