Who are 5-Fluoracil's main competitors?

Direct comparators (same drug class / molecular target / therapeutic area): Xeloda, Fudr, Folic Acid, oxaliplatin plus capecitabine, Irinotecan, 5FU, leucovorin, Phthalin.

How often does this brief refresh?

Every 30 minutes from primary sources (FDA, EMA, MHRA, PMDA, ClinicalTrials.gov, USPTO). Subscribe to the RSS feed below for push alerts.

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Subscribe to /feed/ci/5-fluoracil.xml in any RSS reader (Feedly, Inoreader, NewsBlur). Every regulatory action, trial readout, or patent event lands in your feed automatically.

Last reviewed 2026-05-14 · How we verify

5-Fluoracil — Competitive Intelligence Brief

5-Fluoracil (5-Fluoracil) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: pyrimidine analog. Area: Oncology.

phase 2 pyrimidine analog thymidylate synthase Oncology Small molecule Live · refreshed every 30 min

Target snapshot

5-Fluoracil (5-Fluoracil) — Servicio de Salud Metropolitano Sur Oriente. 5-Fluorouracil is a thymidylate synthase inhibitor that disrupts DNA synthesis and function.

Comparator set (6 drugs)

Auto-detected by same drug class / molecular target / therapeutic area, ranked by phase + recency. Override with ?vs=slug1,slug2,….

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
5-Fluoracil TARGET	5-Fluoracil	Servicio de Salud Metropolitano Sur Oriente	phase 2	pyrimidine analog	thymidylate synthase
Xeloda	capecitabine	Cheplapharm	marketed	Nucleoside Metabolic Inhibitor [EPC]	Thymidylate synthase	1998-01-01
Fudr	FLOXURIDINE		marketed	Antimetabolite [EPC]	Thymidylate synthase	1970-01-01
Folic Acid	FOLIC ACID	Pfizer	marketed	Vitamin C [EPC]	Thymidylate synthase	1946-01-01
oxaliplatin plus capecitabine	oxaliplatin plus capecitabine	LiNing	marketed	Platinum-based chemotherapy combination	DNA (oxaliplatin); thymidylate synthase (capecitabine/5-FU)
Irinotecan, 5FU, leucovorin	Irinotecan, 5FU, leucovorin	Asan Medical Center	marketed	Chemotherapy combination (topoisomerase I inhibitor + antimetabolite)	Topoisomerase I; thymidylate synthase
Phthalin	PHENOLPHTHALEIN		marketed	phenolphthalein	Thymidylate synthase, Thymidylate synthase

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (pyrimidine analog class)

AstraZeneca · 1 drug in this class
China Medical University, China · 1 drug in this class
Grupo Espanol de Tumores Neuroendocrinos · 1 drug in this class
Japan Clinical Oncology Group · 1 drug in this class
Servicio de Salud Metropolitano Sur Oriente · 1 drug in this class
UNICANCER · 1 drug in this class

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Cite this brief

Drug Landscape (2026). 5-Fluoracil — Competitive Intelligence Brief. https://druglandscape.com/ci/5-fluoracil. Accessed 2026-05-14.

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