[18F]Florbetapir PET imaging — Competitive Intelligence Brief

[18F]Florbetapir PET imaging ([18F]Florbetapir PET imaging) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: PET imaging agent. Area: Neurology.

marketed PET imaging agent Amyloid-beta (Aβ) fibrils Neurology Small molecule

Target snapshot

[18F]Florbetapir PET imaging ([18F]Florbetapir PET imaging) — Institute for Neurodegenerative Disorders. [18F]Florbetapir is a positron emission tomography (PET) imaging agent that binds to amyloid-beta plaques in the brain to visualize amyloid pathology.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
[18F]Florbetapir PET imaging TARGET	[18F]Florbetapir PET imaging	Institute for Neurodegenerative Disorders	marketed	PET imaging agent	Amyloid-beta (Aβ) fibrils
[F-18]-Fludeoxyglucose	[F-18]-Fludeoxyglucose	University of Saskatchewan	marketed	Radiopharmaceutical; PET imaging agent	Glucose transporter (GLUT1); hexokinase
Florbetapir F 18 (18F-AV-45)	Florbetapir F 18 (18F-AV-45)	University of California, San Francisco	marketed	PET imaging agent	Amyloid-beta (Aβ) plaques
Fludeoxyglucose F 18 (FDG)	Fludeoxyglucose F 18 (FDG)	Teva Branded Pharmaceutical Products R&D, Inc.	marketed	Radiopharmaceutical; PET imaging agent	Glucose transporter (GLUT1); hexokinase
PET Scan with [11C]ABP688	PET Scan with [11C]ABP688	Stony Brook University	marketed	PET imaging agent / Radiotracer	mGluR5 (metabotropic glutamate receptor 5)
Neuraceq (florbetaben 18F)	Neuraceq (florbetaben 18F)	Piramal Imaging Limited	marketed	PET imaging agent	Amyloid-beta plaques
Flotufolastat (18F)	Flotufolastat (18F)	Blue Earth Diagnostics	marketed	Folate receptor-targeted PET imaging agent	Folate receptor alpha (FR-α)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (PET imaging agent class)

1. University of California, San Francisco · 2 drugs in this class
2. Central Hospital, Nancy, France · 1 drug in this class
3. Centre hospitalier de l'Université de Montréal (CHUM) · 1 drug in this class
4. Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) · 1 drug in this class
5. Institute for Neurodegenerative Disorders · 1 drug in this class
6. OHSU Knight Cancer Institute · 1 drug in this class
7. Piramal Imaging Limited · 1 drug in this class
8. SOFIE · 1 drug in this class
9. Universidad Central del Caribe · 1 drug in this class
10. University of California, Irvine · 1 drug in this class