[18F]FAPI-74 PET/CT — Competitive Intelligence Brief

[18F]FAPI-74 PET/CT ([18F]FAPI-74 PET/CT) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: PET imaging agent. Area: Oncology.

phase 3 PET imaging agent Fibroblast activation protein (FAP) Oncology Small molecule

Target snapshot

[18F]FAPI-74 PET/CT ([18F]FAPI-74 PET/CT) — SOFIE. This drug is a PET imaging agent that targets the fibroblast activation protein (FAP) for the visualization of tumors.

Comparator set (6 drugs)

Drug	Generic	Sponsor	Phase	Class	Target	Approval / PDUFA
[18F]FAPI-74 PET/CT TARGET	[18F]FAPI-74 PET/CT	SOFIE	phase 3	PET imaging agent	Fibroblast activation protein (FAP)
PET Scan with [11C]ABP688	PET Scan with [11C]ABP688	Stony Brook University	marketed	PET imaging agent / Radiotracer	mGluR5 (metabotropic glutamate receptor 5)
[F-18]-Fludeoxyglucose	[F-18]-Fludeoxyglucose	University of Saskatchewan	marketed	Radiopharmaceutical; PET imaging agent	Glucose transporter (GLUT1); hexokinase
Neuraceq (florbetaben 18F)	Neuraceq (florbetaben 18F)	Piramal Imaging Limited	marketed	PET imaging agent	Amyloid-beta plaques
Flotufolastat (18F)	Flotufolastat (18F)	Blue Earth Diagnostics	marketed	Folate receptor-targeted PET imaging agent	Folate receptor alpha (FR-α)
[18F]Florbetapir PET imaging	[18F]Florbetapir PET imaging	Institute for Neurodegenerative Disorders	marketed	PET imaging agent	Amyloid-beta (Aβ) fibrils
18F-rhPSMA-7.3	18F-rhPSMA-7.3	Hackensack Meridian Health	marketed	PET imaging agent / radiopharmaceutical	PSMA (prostate-specific membrane antigen)

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (PET imaging agent class)

1. University of California, San Francisco · 2 drugs in this class
2. Central Hospital, Nancy, France · 1 drug in this class
3. Centre hospitalier de l'Université de Montréal (CHUM) · 1 drug in this class
4. Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) · 1 drug in this class
5. Institute for Neurodegenerative Disorders · 1 drug in this class
6. OHSU Knight Cancer Institute · 1 drug in this class
7. Piramal Imaging Limited · 1 drug in this class
8. SOFIE · 1 drug in this class
9. Universidad Central del Caribe · 1 drug in this class
10. University of California, Irvine · 1 drug in this class