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14C-paliperidone — Competitive Intelligence Brief
phase 1
Atypical antipsychotic
Dopamine D2 receptor
Neurology
Small molecule
Live · refreshed every 30 min
Target snapshot
14C-paliperidone (14C-paliperidone) — Johnson & Johnson Pharmaceutical Research & Development, L.L.C.. Dopamine D2 receptor antagonist
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| 14C-paliperidone TARGET | 14C-paliperidone | Johnson & Johnson Pharmaceutical Research & Development, L.L.C. | phase 1 | Atypical antipsychotic | Dopamine D2 receptor | |
| Aripiprazole tablet | Aripiprazole tablet | All India Institute of Medical Sciences, Bhubaneswar | marketed | Atypical antipsychotic | Dopamine D2 receptor (partial agonist); Serotonin 5-HT1A receptor (partial agonist); Serotonin 5-HT2A receptor (antagonist) | |
| Risperidone and Ramelteon | Risperidone and Ramelteon | All India Institute of Medical Sciences, Bhubaneswar | marketed | Atypical antipsychotic + melatonin receptor agonist combination | Dopamine D2 receptor, serotonin 5-HT2A receptor, melatonin MT1/MT2 receptors | |
| Quetiapine (drug) | Quetiapine (drug) | Medical University of Vienna | marketed | Atypical antipsychotic | Dopamine D2 receptor, Serotonin 5-HT2A receptor | |
| Aripiprazole; Quetiapine | Aripiprazole; Quetiapine | Taichung Veterans General Hospital | marketed | Atypical antipsychotic combination | Dopamine D2 receptor; Serotonin 5-HT2A receptor; Serotonin 5-HT1A receptor | |
| Lithium carbonate + perospirone hydrochloride | Lithium carbonate + perospirone hydrochloride | Shanghai Mental Health Center | marketed | Mood stabilizer + atypical antipsychotic combination | Inositol monophosphatase, GSK-3 (lithium); dopamine D2 receptor, serotonin 5-HT2A receptor (perospirone) | |
| sodium valproate with Clozapine | sodium valproate with Clozapine | Shanghai Mental Health Center | marketed | Antipsychotic + mood stabilizer combination | Dopamine D2 receptor, serotonin 5-HT2A receptor, GABA pathways, histone deacetylase |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Atypical antipsychotic class)
- Shanghai Mental Health Center · 10 drugs in this class
- AstraZeneca · 6 drugs in this class
- Otsuka Pharmaceutical Development & Commercialization, Inc. · 5 drugs in this class
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C. · 4 drugs in this class
- Eli Lilly and Company · 4 drugs in this class
- Otsuka Pharmaceutical Co., Ltd. · 3 drugs in this class
- Medical University of Vienna · 2 drugs in this class
- Organon and Co · 2 drugs in this class
- Chengdu Kanghong Pharmaceutical Group Co., Ltd. · 2 drugs in this class
- H. Lundbeck A/S · 2 drugs in this class
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Cite this brief
Drug Landscape (2026). 14C-paliperidone — Competitive Intelligence Brief. https://druglandscape.com/ci/14c-paliperidone. Accessed 2026-06-10.
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