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β-1,3/1,6-D-glucan — Competitive Intelligence Brief

β-1,3/1,6-D-glucan (β-1,3/1,6-D-glucan) competitive landscape: 6 comparators, recent regulatory actions, upcoming PDUFA, patent timeline. Class: Immunomodulator; biological response modifier. Area: Immunology; Infectious Disease.

marketed Immunomodulator; biological response modifier Dectin-1 (β-glucan receptor); Complement receptor 3 (CR3) Immunology; Infectious Disease Small molecule Live · refreshed every 30 min

Target snapshot

β-1,3/1,6-D-glucan (β-1,3/1,6-D-glucan) — Al-Azhar University. β-1,3/1,6-D-glucan activates innate immune cells by binding to pattern recognition receptors, enhancing immune response and antimicrobial activity.

Comparator set (6 drugs)

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DrugGenericSponsorPhaseClassTargetApproval / PDUFA
β-1,3/1,6-D-glucan TARGET β-1,3/1,6-D-glucan Al-Azhar University marketed Immunomodulator; biological response modifier Dectin-1 (β-glucan receptor); Complement receptor 3 (CR3)
Interferon-Alpha Interferon-Alpha University of Birmingham marketed Cytokine; Immunomodulator Interferon-alpha receptor (IFNAR)
PAD combination PAD combination Cooperative Study Group A for Hematology marketed Combination therapy (proteasome inhibitor + immunomodulatory agent + corticosteroid) 26S proteasome; cereblon (CRBN); glucocorticoid receptor
BG00012 (DMF) BG00012 (DMF) Biogen marketed Fumaric acid ester; immunomodulator Nrf2 (nuclear factor erythroid 2-related factor 2)
Drug: Carfilzomib + Lenalidomide + Dexamethasone Drug: Carfilzomib + Lenalidomide + Dexamethasone Amgen marketed Proteasome inhibitor + Immunomodulatory agent + Corticosteroid combination 20S proteasome (carfilzomib); cereblon/CRBN (lenalidomide); glucocorticoid receptor (dexamethasone)
histamine dihydrochloride and IL-2 histamine dihydrochloride and IL-2 Cytovia, Inc. marketed Immunomodulator combination Histamine receptors (H1, H2, H3, H4) and IL-2 receptor
Single Dose of Hydroxychloroquine Single Dose of Hydroxychloroquine Shahid Beheshti University of Medical Sciences marketed Antimalarial immunomodulator Toll-like receptors (TLR); lysosomal pH modulation

Recent regulatory actions (last 90 days)

No regulatory actions in the last 90 days for this set.

Upcoming PDUFA dates (next 180 days)

No PDUFA dates in the next 180 days for this set.

Patent timeline (forward window)

No upcoming patent expiries for this set.

Sponsor landscape (Immunomodulator; biological response modifier class)

  1. Al-Azhar University · 1 drug in this class

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Cite this brief

Drug Landscape (2026). β-1,3/1,6-D-glucan — Competitive Intelligence Brief. https://druglandscape.com/ci/1-3-1-6-d-glucan. Accessed 2026-05-16.

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