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β-1,3/1,6-D-glucan — Competitive Intelligence Brief
marketed
Immunomodulator; biological response modifier
Dectin-1 (β-glucan receptor); Complement receptor 3 (CR3)
Immunology; Infectious Disease
Small molecule
Live · refreshed every 30 min
Target snapshot
β-1,3/1,6-D-glucan (β-1,3/1,6-D-glucan) — Al-Azhar University. β-1,3/1,6-D-glucan activates innate immune cells by binding to pattern recognition receptors, enhancing immune response and antimicrobial activity.
Comparator set (6 drugs)
| Drug | Generic | Sponsor | Phase | Class | Target | Approval / PDUFA |
|---|---|---|---|---|---|---|
| β-1,3/1,6-D-glucan TARGET | β-1,3/1,6-D-glucan | Al-Azhar University | marketed | Immunomodulator; biological response modifier | Dectin-1 (β-glucan receptor); Complement receptor 3 (CR3) | |
| Interferon-Alpha | Interferon-Alpha | University of Birmingham | marketed | Cytokine; Immunomodulator | Interferon-alpha receptor (IFNAR) | |
| PAD combination | PAD combination | Cooperative Study Group A for Hematology | marketed | Combination therapy (proteasome inhibitor + immunomodulatory agent + corticosteroid) | 26S proteasome; cereblon (CRBN); glucocorticoid receptor | |
| BG00012 (DMF) | BG00012 (DMF) | Biogen | marketed | Fumaric acid ester; immunomodulator | Nrf2 (nuclear factor erythroid 2-related factor 2) | |
| Drug: Carfilzomib + Lenalidomide + Dexamethasone | Drug: Carfilzomib + Lenalidomide + Dexamethasone | Amgen | marketed | Proteasome inhibitor + Immunomodulatory agent + Corticosteroid combination | 20S proteasome (carfilzomib); cereblon/CRBN (lenalidomide); glucocorticoid receptor (dexamethasone) | |
| histamine dihydrochloride and IL-2 | histamine dihydrochloride and IL-2 | Cytovia, Inc. | marketed | Immunomodulator combination | Histamine receptors (H1, H2, H3, H4) and IL-2 receptor | |
| Single Dose of Hydroxychloroquine | Single Dose of Hydroxychloroquine | Shahid Beheshti University of Medical Sciences | marketed | Antimalarial immunomodulator | Toll-like receptors (TLR); lysosomal pH modulation |
Recent regulatory actions (last 90 days)
Upcoming PDUFA dates (next 180 days)
Patent timeline (forward window)
Sponsor landscape (Immunomodulator; biological response modifier class)
- Al-Azhar University · 1 drug in this class
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Cite this brief
Drug Landscape (2026). β-1,3/1,6-D-glucan — Competitive Intelligence Brief. https://druglandscape.com/ci/1-3-1-6-d-glucan. Accessed 2026-05-16.
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