{"id":"zushima-plaster-with-high-dose","safety":{"commonSideEffects":[{"rate":null,"effect":"Skin irritation or contact dermatitis"},{"rate":null,"effect":"Local allergic reactions"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"As a high-dose plaster formulation, Zushima delivers concentrated herbal ingredients through the skin to target localized pain and inflammation. The specific active constituents and their molecular mechanisms are characteristic of traditional Chinese medicine preparations, which typically work through multiple pathways including anti-inflammatory, analgesic, and circulation-promoting effects. The transdermal delivery system allows sustained release of therapeutic compounds to affected areas.","oneSentence":"Zushima plaster is a traditional Chinese medicine transdermal patch formulation designed to provide pain relief and anti-inflammatory effects through topical delivery of herbal active compounds.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T00:16:54.242Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Localized pain and inflammation (specific indications not fully documented in available sources)"}]},"trialDetails":[{"nctId":"NCT02770950","phase":"PHASE4","title":"Zushima Plaster for Treating Knee Osteoarthritis","status":"COMPLETED","sponsor":"Guang'anmen Hospital of China Academy of Chinese Medical Sciences","startDate":"2016-05","conditions":"Osteoarthritis","enrollment":396}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Zushima plaster with high dose","genericName":"Zushima plaster with high dose","companyName":"Guang'anmen Hospital of China Academy of Chinese Medical Sciences","companyId":"guang-anmen-hospital-of-china-academy-of-chinese-medical-sciences","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Zushima plaster is a traditional Chinese medicine transdermal patch formulation designed to provide pain relief and anti-inflammatory effects through topical delivery of herbal active compounds. Used for Localized pain and inflammation (specific indications not fully documented in available sources).","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}