{"id":"zuraprep-without-70-ipa","safety":{"commonSideEffects":[{"rate":"null","effect":"Skin irritation"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"It achieves this by denaturing proteins and disrupting cell membranes of microorganisms, thereby inhibiting their growth and replication. This mechanism is effective against a broad spectrum of bacteria, viruses, and fungi.","oneSentence":"ZuraPrep without 70% IPA is a topical antiseptic solution that helps prevent surgical site infections by reducing microbial load.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T01:41:32.230Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Prevention of surgical site infections"}]},"trialDetails":[{"nctId":"NCT03782103","phase":"PHASE3","title":"In-vivo Efficacy of Patient Preoperative Prep, ZuraPrep (ZP)","status":"COMPLETED","sponsor":"Zurex Pharma, Inc.","startDate":"2019-01-25","conditions":"Surgical Skin Preparation","enrollment":156},{"nctId":"NCT02831998","phase":"PHASE3","title":"In-vivo Efficacy of Patient Preoperative Prep","status":"COMPLETED","sponsor":"Zurex Pharma, Inc.","startDate":"2016-07-27","conditions":"Surgical Skin Preparation","enrollment":440},{"nctId":"NCT02831816","phase":"PHASE3","title":"Clinical Evaluation of Patient Preoperative Prep","status":"COMPLETED","sponsor":"Zurex Pharma, Inc.","startDate":"2016-08-03","conditions":"Surgical Skin Preparation","enrollment":640},{"nctId":"NCT02578771","phase":"PHASE3","title":"Pilot Clinical Evaluation to Characterize in Vivo Effects of Topically Applied ZuraPrep & ZuraPrep Vehicle","status":"COMPLETED","sponsor":"Zurex Pharma, Inc.","startDate":"2015-10","conditions":"Surgical Site Infection","enrollment":123},{"nctId":"NCT02221232","phase":"PHASE2","title":"Efficacy Study to Evaluate Antimicrobial Effectiveness of ZuraPrep™","status":"TERMINATED","sponsor":"Zurex Pharma, Inc.","startDate":"2014-08","conditions":"Surgical Site Infection","enrollment":64},{"nctId":"NCT02160587","phase":"PHASE1","title":"Safety Study to Evaluate the Contact Sensitizing Potential of Topically Applied ZuraPrep™ and ZuraPrep™ Without IPA","status":"COMPLETED","sponsor":"Zurex Pharma, Inc.","startDate":"2014-07","conditions":"Surgical Site Infection","enrollment":208},{"nctId":"NCT02160574","phase":"PHASE1","title":"Safety Study to Evaluate the Cumulative Irritation Potential of Topically Applied ZuraPrep™ and ZuraPrep™ Without IPA","status":"COMPLETED","sponsor":"Zurex Pharma, Inc.","startDate":"2014-06","conditions":"Surgical Site Infection","enrollment":40}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["ZuraPrep Vehicle"],"phase":"phase_3","status":"active","brandName":"ZuraPrep without 70% IPA","genericName":"ZuraPrep without 70% IPA","companyName":"Zurex Pharma, Inc.","companyId":"zurex-pharma-inc","modality":"Small molecule","firstApprovalDate":"","aiSummary":"ZuraPrep is a topical antimicrobial agent used for surgical skin preparation to reduce the risk of surgical site infections. It has been clinically evaluated for its efficacy in in-vivo studies, with results from the study \"In-vivo Efficacy of Patient Preoperative Prep\" (NCT02831998) indicating its effectiveness in this application.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}