{"id":"zoster-vaccine-live-amp","safety":{"commonSideEffects":[{"rate":"null","effect":"Pain, redness, or swelling at the injection site"},{"rate":"null","effect":"Fatigue"},{"rate":"null","effect":"Headache"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"This vaccine contains a live, attenuated form of the varicella-zoster virus, which is the same virus that causes chickenpox and shingles. When administered, it triggers an immune response that helps the body recognize and fight the virus, providing protection against future infections.","oneSentence":"The Zoster Vaccine, Live (AMP) works by stimulating the body's immune system to produce a specific response against the varicella-zoster virus.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T01:41:31.216Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Prevention of herpes zoster (shingles) in adults 50 years of age and older"}]},"trialDetails":[{"nctId":"NCT06313762","phase":"NA","title":"Use of Virtual Reality in the Reduction of Pain After the Administration of Vaccines Among Children in Primary Care Centers.","status":"COMPLETED","sponsor":"Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina","startDate":"2022-01-18","conditions":"Pain, Pediatrics, Vaccination","enrollment":300},{"nctId":"NCT01536405","phase":"PHASE3","title":"Safety, Tolerability, and Immunogenicity of Measles, Mumps, Rubella, and Varicella (MMRV) Vaccine Made With an Alternative Manufacturing Process (AMP)(V221-027)","status":"COMPLETED","sponsor":"Merck Sharp & Dohme LLC","startDate":"2012-06-05","conditions":"Measles, Mumps, Rubella","enrollment":1412},{"nctId":"NCT01505647","phase":"PHASE3","title":"Safety and Immunogenicity of Zoster Vaccine (ZOSTAVAX™) Made With an Alternative Manufacturing Process (AMP) (V211-042 AM1)","status":"COMPLETED","sponsor":"Merck Sharp & Dohme LLC","startDate":"2012-04","conditions":"Herpes Zoster, Shingles","enrollment":498}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"Zoster Vaccine, Live (AMP)","genericName":"Zoster Vaccine, Live (AMP)","companyName":"Merck Sharp & Dohme LLC","companyId":"merck","modality":"Biologic","firstApprovalDate":"","aiSummary":"The Zoster Vaccine, Live (AMP) works by stimulating the body's immune system to produce a specific response against the varicella-zoster virus. Used for Prevention of herpes zoster (shingles) in adults 50 years of age and older.","enrichmentLevel":3,"visitCount":1,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}