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The mechanism is thought to underlie its efficacy in treating depression and anxiety disorders.","oneSentence":"Zoloft selectively blocks the reuptake of serotonin in the brain, increasing serotonin availability at synapses.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T00:16:46.916Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Major depressive disorder"},{"name":"Obsessive-compulsive disorder"},{"name":"Panic disorder"},{"name":"Post-traumatic stress disorder"},{"name":"Social anxiety disorder"},{"name":"Generalized anxiety disorder"},{"name":"Premenstrual dysphoric disorder"}]},"_fixedFields":["pubmed(2148)"],"trialDetails":[{"nctId":"NCT07015944","phase":"NA","title":"Moving on After Breast Cancer Trial for Depressed Breast Cancer Survivors in Pakistan","status":"RECRUITING","sponsor":"Pakistan Institute of Living and Learning","startDate":"2025-06-13","conditions":"Major Depressive Disorder (MDD), Breast Cancer 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