{"id":"ziyinxiehuo-granules-herbs","safety":{"commonSideEffects":[]},"_chembl":{"chemblId":"CHEMBL2108094","moleculeType":"Unknown"},"_dailymed":null,"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"This herbal granule preparation combines multiple traditional Chinese medicinal herbs to address patterns of yin deficiency with heat excess, commonly used in pediatric practice. The formulation works through the synergistic action of its herbal components to reduce fever, soothe irritability, and promote cooling of the body according to traditional Chinese medicine theory. It is typically used for acute febrile conditions and heat-related symptoms in children.","oneSentence":"Ziyinxiehuo Granules is a traditional Chinese herbal medicine formulation designed to clear heat, nourish yin, and reduce internal heat symptoms in children.","_ai_confidence":"low"},"_scrapedAt":"2026-03-28T00:16:35.100Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Pediatric fever and heat-related symptoms"},{"name":"Acute febrile conditions in children"}]},"trialDetails":[{"nctId":"NCT06510764","phase":"PHASE3","title":"A Trial of Chinese Traditional Medicine Combining With Intradermal Acupuncture for Treating Precocious Puberty","status":"RECRUITING","sponsor":"Children's Hospital of Fudan University","startDate":"2024-09-15","conditions":"Precocious Puberty, Treatment, Alternative Medicine","enrollment":170},{"nctId":"NCT03963752","phase":"PHASE4","title":"Clinical Trial of Rapid Progressive Central Precocious Puberty With Integrative Chinese and Western Medicine","status":"COMPLETED","sponsor":"Children's Hospital of Fudan University","startDate":"2019-08-15","conditions":"Idiopathic Precocious Puberty","enrollment":126},{"nctId":"NCT02650141","phase":"NA","title":"Clinical Trial of Experienced Chinese Herbal Formulas on Different Types of Precocious Puberty","status":"COMPLETED","sponsor":"Children's Hospital of Fudan University","startDate":"2013-04","conditions":"Precocious Puberty","enrollment":143}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":223,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":["nourishing\"Yin\"-removing\"Fire\" Granules"],"phase":"marketed","status":"active","brandName":"Ziyinxiehuo Granules Herbs","genericName":"Ziyinxiehuo Granules Herbs","companyName":"Children's Hospital of Fudan University","companyId":"children-s-hospital-of-fudan-university","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Ziyinxiehuo Granules is a traditional Chinese herbal medicine formulation designed to clear heat, nourish yin, and reduce internal heat symptoms in children. Used for Pediatric fever and heat-related symptoms, Acute febrile conditions in children.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":false,"trials":true,"score":3}}