{"id":"zingiber-officinalis","safety":{"commonSideEffects":[{"rate":null,"effect":"Gastrointestinal upset (heartburn, abdominal discomfort)"},{"rate":null,"effect":"Allergic reactions (rare)"},{"rate":null,"effect":"Bleeding risk (at high doses, due to antiplatelet effects)"}]},"_chembl":null,"_dailymed":{"setId":"84e268e5-ba68-4ad6-84d4-d799c4ea91ee","title":"UPPER GI AND ENZYME RESTORATION (ACETICUM ACIDUM, AGARICUS MUSCARIUS, ALOE, ANTIMONIUM CRUDUM, ARGENTUM NITRICUM, CARBO VEGETABILIS, CARDUUS MARIANUS, CHELIDONIUM MAJUS, CHENOPODIUM ANTHELMINTICUM, CINCHONA OFFICINALIS, GRAPHITES, IPECACUANHA, LAC DEFLORATUM, MENTHA PIPERITA, NUX VOMICA, SECALE CORNUTUM, TANACETUM VULGARE, TEUCRIUM MARUM AND ZINGIBER OFFICINALE.) LIQUID [KING BIO INC.]"},"mechanism":{"_ai_source":"claude-haiku-4.5","explanation":"Zingiber officinalis (ginger) exerts anti-inflammatory effects primarily through inhibition of NF-κB signaling and reduction of pro-inflammatory cytokines such as TNF-α and IL-6. The rhizome also possesses antioxidant properties and may enhance gastrointestinal motility, contributing to its traditional use in nausea and digestive complaints.","oneSentence":"Ginger root contains active compounds (gingerols and shogaols) that inhibit inflammatory mediators and modulate immune responses.","_ai_confidence":"medium"},"_scrapedAt":"2026-03-28T04:29:40.823Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Nausea and vomiting (including chemotherapy-induced and post-operative)"},{"name":"Osteoarthritis and rheumatoid arthritis"},{"name":"Dyspepsia and gastrointestinal discomfort"},{"name":"Migraine prophylaxis"}]},"trialDetails":[{"nctId":"NCT07475299","phase":"NA","title":"Synbiotic Supplement With Botanical Extracts for Gut Microbiota Balance in Irritable Bowel Syndrome","status":"NOT_YET_RECRUITING","sponsor":"Iuliu Hatieganu University of Medicine and Pharmacy","startDate":"2026-04","conditions":"Irritable Bowel Syndrome (IBS)","enrollment":8},{"nctId":"NCT02488252","phase":"PHASE2, PHASE3","title":"Semi-individualised Chinese Medicine Treatment as an Adjuvant Management for Diabetic Nephropathy","status":"UNKNOWN","sponsor":"The University of Hong Kong","startDate":"2015-07","conditions":"Diabetic Nephropathies","enrollment":148},{"nctId":"NCT03449303","phase":"NA","title":"Chemotherapy-Induced Peripheral Neuropathy-Essential Oil Intervention","status":"COMPLETED","sponsor":"Augusta University","startDate":"2018-06-25","conditions":"Breast Cancer, Peripheral Neuropathies","enrollment":26},{"nctId":"NCT00676975","phase":"PHASE2","title":"The Efficacy of Tradition Chinese Medicine in Patients With Irritable Bowel Syndrome","status":"COMPLETED","sponsor":"Chinese University of Hong Kong","startDate":"2008-05-26","conditions":"Irritable Bowel Syndrome","enrollment":104},{"nctId":"NCT00537875","phase":"NA","title":"Evaluation of the Effect of Zingiber Officinalis on Nausea and Vomiting in Patients Receiving Cisplatin Based Regimens","status":"COMPLETED","sponsor":"National Research Institute of Tuberculosis and Lung Disease, Iran","startDate":"2007-09","conditions":"Nausea, Vomiting","enrollment":36},{"nctId":"NCT01321632","phase":"PHASE1","title":"Efficacy of Zingiber Officinalis (Homoeopathic Medicine) in Treatment of Acne Vulgaris","status":"COMPLETED","sponsor":"Miglani, Anjali","startDate":"2011-03","conditions":"Acne Vulgaris","enrollment":32}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":75,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"marketed","status":"active","brandName":"Zingiber officinalis","genericName":"Zingiber officinalis","companyName":"Miglani, Anjali","companyId":"miglani-anjali","modality":"Small molecule","firstApprovalDate":"","aiSummary":"Ginger root contains active compounds (gingerols and shogaols) that inhibit inflammatory mediators and modulate immune responses. Used for Nausea and vomiting (including chemotherapy-induced and post-operative), Osteoarthritis and rheumatoid arthritis, Dyspepsia and gastrointestinal discomfort.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":0,"withResults":0},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}