{"id":"zilbrix-hib","safety":{"commonSideEffects":[{"rate":"null","effect":"Pain, redness, or swelling at the injection site"},{"rate":"null","effect":"Fever"},{"rate":"null","effect":"Irritability"}]},"_chembl":null,"_dailymed":null,"mechanism":{"_ai_source":"groq-llama-8b","explanation":"It works by stimulating the body's immune system to produce antibodies against these pathogens, thereby preventing infection. The vaccine is composed of inactivated or attenuated pathogens or their components, which are combined with a carrier protein to enhance immune response. This conjugate vaccine is administered via injection to provide long-lasting immunity against these serious bacterial infections.","oneSentence":"Zilbrix-Hib is a conjugate vaccine that protects against Haemophilus influenzae type b and diphtheria, tetanus, and pertussis.","_ai_confidence":"high"},"_scrapedAt":"2026-03-28T01:41:24.246Z","_scrapedBy":"cloudflare-swarm","_wikipedia":null,"indications":{"approved":[{"name":"Haemophilus influenzae type b disease prevention"},{"name":"Diphtheria prevention"},{"name":"Tetanus prevention"},{"name":"Pertussis prevention"}]},"trialDetails":[{"nctId":"NCT00678301","phase":"PHASE3","title":"Primary Vaccination Course in Children Receiving the Pneumococcal Vaccine GSK 1024850A, Zilbrix™ Hib and Polio Sabin™","status":"COMPLETED","sponsor":"GlaxoSmithKline","startDate":"2008-06-18","conditions":"Infections, Streptococcal","enrollment":365},{"nctId":"NCT01106092","phase":"PHASE2","title":"Study to Evaluate the Immunogenicity and Reactogenicity of a Booster Dose of GSK2036874A Vaccine in Healthy Toddlers","status":"COMPLETED","sponsor":"GlaxoSmithKline","startDate":"2010-05-13","conditions":"Haemophilus Influenzae Type b, Tetanus, Hepatitis B","enrollment":312},{"nctId":"NCT00473668","phase":"PHASE3","title":"Non-inferiority of GSK Biologicals' DTPw-HBV/Hib Compared to Two Formulations of GSK Biologicals' DTPw-HBV/Hib","status":"COMPLETED","sponsor":"GlaxoSmithKline","startDate":"2007-06-01","conditions":"Whole Cell Pertussis, Haemophilus Influenzae Type b, Tetanus","enrollment":300}],"_emaApprovals":[],"_faersSignals":[],"_approvalHistory":[],"publicationCount":0,"rwe":[],"genericFilers":[],"relatedDrugs":[],"labelChanges":[],"biosimilarFilings":[],"pricing":[],"formularyStatus":[],"manufacturing":[],"companionDiagnostics":[],"competitors":[],"timeline":[],"patents":[],"ownershipHistory":[],"trials":[],"biosimilars":[],"latestUpdates":[],"references":[],"tags":[],"ecosystem":[],"genericManufacturerList":[],"offLabel":[],"developmentCodes":[],"aliases":[],"phase":"phase_3","status":"active","brandName":"Zilbrix-Hib","genericName":"Zilbrix-Hib","companyName":"GlaxoSmithKline","companyId":"gsk","modality":"Biologic","firstApprovalDate":"","aiSummary":"Zilbrix-Hib is a conjugate vaccine that protects against Haemophilus influenzae type b and diphtheria, tetanus, and pertussis. Used for Haemophilus influenzae type b disease prevention, Diphtheria prevention, Tetanus prevention.","enrichmentLevel":3,"visitCount":0,"trialStats":{"total":1,"withResults":1},"verificationStatus":"verified","dataCompleteness":{"mechanism":true,"indications":true,"safety":true,"trials":true,"score":4}}